Update genesets with new scDEGs, including new Leu set

genesets/DEG_BE.csv

@@ -5,8 +5,8 @@
 "4","KRT23"
 "5","RGCC"
 "6","KRT5"
-"7","KRT15"
-"8","DKK1"
+"7","DKK1"
+"8","KRT15"
 "9","LAYN"
 "10","CLDN1"
 "11","KRT17"
@@ -15,8 +15,8 @@
 "14","PDCD5"
 "15","MYC"
 "16","PTRF"
-"17","KRT7"
-"18","NCL"
+"17","NCL"
+"18","KRT7"
 "19","NPM1"
 "20","TUBB4B"
 "21","ATP1B3"
@@ -33,6 +33,4 @@
 "32","RANBP1"
 "33","SRM"
 "34","SSB"
-"35","SNRPD1"
-"36","HBEGF"
-"37","DEFB1"
+"35","DEFB1"

genesets/DEG_Endo.csv

@@ -17,65 +17,62 @@
 "16","CALCRL"
 "17","CFLAR"
 "18","ZNF385D"
-"19","HLA-DQB1"
-"20","ASPH"
-"21","VWF"
-"22","TPM3"
-"23","HLA-DPA1"
-"24","ECSCR.1"
-"25","PLVAP"
-"26","ADGRL4"
-"27","S100A10"
-"28","SLC7A11"
-"29","NQO1"
-"30","MSN"
-"31","HLA-DQA1"
-"32","RHOC"
-"33","ARPC1B"
-"34","NOP10"
-"35","BACE2"
-"36","FXYD5"
-"37","TM4SF18"
-"38","HLA-DPB1"
-"39","RDX"
-"40","CLIC1"
-"41","SWAP70"
-"42","DUSP6"
-"43","MRPL33"
-"44","PNP"
-"45","MED24"
-"46","CNKSR3"
-"47","LMO2"
-"48","MGST2"
-"49","PPFIBP1"
-"50","COL15A1"
-"51","NEURL1B"
-"52","CDC37"
-"53","RNASE1"
-"54","ST3GAL6"
-"55","ZEB1"
-"56","RAPGEF5"
-"57","GCLM"
-"58","SOX17"
-"59","RPS18"
-"60","AP1S2"
-"61","CDC42EP3"
-"62","IL3RA"
-"63","EMCN"
-"64","RHOJ"
-"65","FLT1"
-"66","CD59"
-"67","HSPA8"
-"68","PGF"
-"69","CARHSP1"
-"70","ITM2A"
-"71","ITGA2"
-"72","RAB13"
-"73","ARPC5L"
-"74","TNPO1"
-"75","UPP1"
-"76","SH3BP5"
-"77","INSR"
-"78","MMP10"
-"79","CXCL2"
-"80","ANGPT2"
+"19","ASPH"
+"20","VWF"
+"21","TPM3"
+"22","ECSCR.1"
+"23","PLVAP"
+"24","ADGRL4"
+"25","S100A10"
+"26","NQO1"
+"27","SLC7A11"
+"28","MSN"
+"29","RHOC"
+"30","NOP10"
+"31","BACE2"
+"32","TM4SF18"
+"33","RDX"
+"34","CLIC1"
+"35","SWAP70"
+"36","DUSP6"
+"37","MRPL33"
+"38","PNP"
+"39","MED24"
+"40","CNKSR3"
+"41","LMO2"
+"42","MGST2"
+"43","PPFIBP1"
+"44","COL15A1"
+"45","NEURL1B"
+"46","CDC37"
+"47","RNASE1"
+"48","ZEB1"
+"49","ST3GAL6"
+"50","RAPGEF5"
+"51","GCLM"
+"52","SOX17"
+"53","RPS18"
+"54","CDC42EP3"
+"55","EMCN"
+"56","IL3RA"
+"57","RHOJ"
+"58","FLT1"
+"59","CD59"
+"60","HSPA8"
+"61","AFAP1L1"
+"62","HLA-B"
+"63","TRIB3"
+"64","PGF"
+"65","CARHSP1"
+"66","ITM2A"
+"67","ITGA2"
+"68","RAB13"
+"69","ARPC5L"
+"70","TNPO1"
+"71","SH3BP5"
+"72","KLF2"
+"73","JAG1"
+"74","INSR"
+"75","MMP10"
+"76","CXCL2"
+"77","ANGPT2"

genesets/DEG_Epi.csv

 "","x"
 "1","TACSTD2"
 "2","KRT19"
-"3","LCN2"
-"4","AQP3"
-"5","SFN"
-"6","S100P"
-"7","AZGP1"
-"8","KRT8"
-"9","CD24"
-"10","SPINT2"
-"11","KRT18"
-"12","KLF5"
-"13","AGR2"
-"14","S100A14"
-"15","GDF15"
-"16","S100A16"
-"17","ACTG1"
-"18","CLDN7"
-"19","ACTB"
-"20","GSTP1"
-"21","ANXA2"
-"22","HMGA1"
-"23","CXCL17"
-"24","PERP"
-"25","LAMB3"
-"26","ANXA11"
-"27","PLAU"
-"28","S100A10"
-"29","S100A11"
-"30","PHLDA2"
-"31","SLC14A1"
-"32","TSPO"
-"33","CXCL16"
-"34","MRPS6"
-"35","MAL2"
-"36","LAMC2"
-"37","ANXA3"
-"38","EPCAM"
-"39","VAMP8"
-"40","CD9"
-"41","CD47"
-"42","TXNIP"
-"43","IFNGR2"
-"44","ARHGAP29"
-"45","MALL"
-"46","MYL12B"
-"47","TALDO1"
-"48","GPX2"
-"49","EZR"
-"50","SDCBP2"
-"51","PPDPF"
-"52","MPZL2"
-"53","GALNT3"
-"54","JUP"
-"55","LIMA1"
-"56","SH3BGRL3"
-"57","PHLDA3"
-"58","NDUFV2"
-"59","MYO6"
-"60","ACTN4"
-"61","TNFRSF21"
-"62","HEBP2"
-"63","TPM4"
-"64","DSP"
-"65","HINT1"
-"66","MAST4"
-"67","EHF"
-"68","MAP3K13"
-"69","DRAP1"
-"70","MET"
-"71","SDC4"
-"72","KLK11"
-"73","SH3YL1"
-"74","F3"
+"3","AQP3"
+"4","SFN"
+"5","S100P"
+"6","AZGP1"
+"7","KRT8"
+"8","CD24"
+"9","SPINT2"
+"10","KRT18"
+"11","KLF5"
+"12","AGR2"
+"13","S100A14"
+"14","S100A16"
+"15","ACTG1"
+"16","CLDN7"
+"17","ACTB"
+"18","GSTP1"
+"19","ANXA2"
+"20","HMGA1"
+"21","PERP"
+"22","LAMB3"
+"23","ANXA11"
+"24","PLAU"
+"25","S100A10"
+"26","C15orf48"
+"27","S100A11"
+"28","PHLDA2"
+"29","SLC14A1"
+"30","TSPO"
+"31","CXCL16"
+"32","MRPS6"
+"33","MAL2"
+"34","LAMC2"
+"35","ANXA3"
+"36","EPCAM"
+"37","VAMP8"
+"38","CD9"
+"39","CD47"
+"40","TXNIP"
+"41","IFNGR2"
+"42","ARHGAP29"
+"43","SERINC2"
+"44","MYL12B"
+"45","TALDO1"
+"46","EZR"
+"47","PPDPF"
+"48","MPZL2"
+"49","GALNT3"
+"50","JUP"
+"51","LIMA1"
+"52","SH3BGRL3"
+"53","PHLDA3"
+"54","NDUFV2"
+"55","MYO6"
+"56","ACTN4"
+"57","TNFRSF21"
+"58","HEBP2"
+"59","TPM4"
+"60","DSP"
+"61","HINT1"
+"62","MAST4"
+"63","EHF"
+"64","MAP3K13"
+"65","DRAP1"
+"66","MET"
+"67","SDC4"
+"68","KLK11"
+"69","SH3YL1"
+"70","F3"

genesets/DEG_Fib.csv

@@ -13,24 +13,24 @@
 "12","CFD"
 "13","PDPN"
 "14","FGF2"
-"15","ANXA5"
-"16","MFAP4"
-"17","G0S2"
-"18","RHOBTB3"
-"19","HMGA1"
+"15","MEG3"
+"16","ANXA5"
+"17","MFAP4"
+"18","G0S2"
+"19","RHOBTB3"
 "20","LTBP4"
-"21","TNFAIP6"
-"22","SFRP2"
-"23","PLAUR"
-"24","S100A11"
-"25","FGF7"
-"26","SNCA"
-"27","PLAT"
-"28","KCNK1"
-"29","TNFRSF12A"
-"30","DNAJB9"
-"31","MPZL1"
-"32","ATP2B1"
+"21","HMGA1"
+"22","TNFAIP6"
+"23","SFRP2"
+"24","PLAUR"
+"25","S100A11"
+"26","FGF7"
+"27","SNCA"
+"28","PLAT"
+"29","KCNK1"
+"30","TNFRSF12A"
+"31","DNAJB9"
+"32","MPZL1"
 "33","FBLN2"
 "34","SEC62"
 "35","LPAR1"
@@ -40,33 +40,33 @@
 "39","PDGFRA"
 "40","REEP5"
 "41","CLU"
-"42","RND3"
-"43","ARSG"
+"42","ARSG"
+"43","RND3"
 "44","SCARB2"
 "45","SPOCK3"
 "46","CTSK"
 "47","GJA1"
-"48","NPC2"
-"49","VCAN"
-"50","SLC25A37"
-"51","DPT"
-"52","MYDGF"
-"53","CXCL8"
-"54","UAP1"
-"55","PDIA6"
-"56","HSP90B1"
-"57","HSPA5"
-"58","SPON2"
-"59","MATN2"
-"60","GPM6B"
+"48","VCAN"
+"49","SLC25A37"
+"50","DPT"
+"51","MYDGF"
+"52","CXCL8"
+"53","UAP1"
+"54","PDIA6"
+"55","HSP90B1"
+"56","HSPA5"
+"57","SPON2"
+"58","MATN2"
+"59","GPM6B"
+"60","CREB5"
 "61","EFEMP1"
-"62","CREB5"
-"63","MANF"
-"64","FST"
+"62","MANF"
+"63","FST"
+"64","CXCL1"
 "65","IL33"
 "66","MGP"
-"67","SDF2L1"
-"68","CD55"
+"67","CD55"
+"68","SDF2L1"
 "69","GSN"
 "70","SFRP1"
 "71","THBS2"

genesets/DEG_LE.csv

@@ -19,10 +19,10 @@
 "18","IL6ST"
 "19","VMP1"
 "20","SMIM14"
-"21","CLDN4"
-"22","H2AFJ"
-"23","TMPRSS2"
-"24","HMGCS1"
+"21","H2AFJ"
+"22","CLDN4"
+"23","HMGCS1"
+"24","TMPRSS2"
 "25","CIB1"
 "26","EMP1"
 "27","DBI"
@@ -33,51 +33,52 @@
 "32","GP2"
 "33","ELL2"
 "34","ALDH1A3"
-"35","CRYAB"
+"35","IDH2"
 "36","PPP3CA"
-"37","IDH2"
-"38","PMEPA1"
-"39","ERRFI1"
-"40","RAB27B"
-"41","UQCRQ"
-"42","FXYD3"
+"37","PMEPA1"
+"38","ERRFI1"
+"39","RAB27B"
+"40","UQCRQ"
+"41","FXYD3"
+"42","CRYAB"
 "43","RPS27L"
 "44","MT1F"
 "45","LMO7"
 "46","SOCS2"
 "47","RNF213"
-"48","SLC44A4"
-"49","SARAF"
-"50","ELOVL5"
-"51","RASEF"
+"48","SARAF"
+"49","ELOVL5"
+"50","RASEF"
+"51","SLC44A4"
 "52","SLC39A6"
-"53","SH3BP4"
-"54","KLK4"
+"53","KLK4"
+"54","SH3BP4"
 "55","GDE1"
 "56","LBH"
 "57","FLJ20021"
 "58","SERF2"
 "59","RDH10"
-"60","FNIP2"
-"61","MALAT1"
-"62","ST6GAL1"
-"63","ABHD2"
-"64","NGFRAP1"
-"65","PDE4B"
-"66","TSTD1"
-"67","SLC12A2"
-"68","PART1"
-"69","MEAF6"
-"70","LCP1"
-"71","BRI3"
-"72","IL1R1"
-"73","MPC2"
-"74","FRMD4B"
-"75","SNRPN"
-"76","F11R"
-"77","ATP1A1"
-"78","SEMA4B"
-"79","ZFP36"
-"80","TGIF1"
-"81","ID1"
+"60","MALAT1"
+"61","ST6GAL1"
+"62","ABHD2"
+"63","NGFRAP1"
+"64","TSTD1"
+"65","PART1"
+"66","LCP1"
+"67","MEAF6"
+"68","SLC12A2"
+"69","IL1R1"
+"70","MPC2"
+"71","SNRPN"
+"72","FRMD4B"
+"73","F11R"
+"74","ATP1A1"
+"75","SEMA4B"
+"76","AIM1"
+"77","MACF1"
+"78","ZFP36"
+"79","TGIF1"
+"80","ID1"
+"81","MALL"
 "82","CEACAM1"
+"83","BIRC3"

genesets/DEG_Leu.csv

+"","x"
+"1","C1QA"
+"2","TYROBP"
+"3","C1QB"
+"4","RGS1"
+"5","FCER1G"
+"6","LAPTM5"
+"7","CCL3"
+"8","EREG"
+"9","GPR183"
+"10","C1QC"
+"11","CST7"
+"12","RNASE6"
+"13","CXCR4"
+"14","SPI1"
+"15","CYTIP"
+"16","CCR7"
+"17","OLR1"
+"18","AIF1"
+"19","PTPRC"
+"20","IGSF6"
+"21","LST1"
+"22","MS4A6A"
+"23","MS4A7"
+"24","ALOX5AP"
+"25","EVI2B"
+"26","SAMSN1"
+"27","CD48"
+"28","LILRB4"
+"29","ITGAX"
+"30","C5AR1"
+"31","VSIG4"
+"32","CD37"
+"33","FCGR2A"
+"34","ST8SIA4"
+"35","ITGB2"
+"36","CD53"
+"37","CSF2RA"
+"38","MS4A4A"
+"39","PLA2G7"
+"40","FGL2"
+"41","CD14"
+"42","FAM26F"
+"43","LY96"
+"44","SERPINB9"
+"45","KYNU"
+"46","FAM49A"
+"47","LYZ"
+"48","ABCA1"
+"49","IFI30"
+"50","SLC16A10"
+"51","GPSM3"
+"52","APOC1"
+"53","SLC11A1"
+"54","TGFBI"
+"55","HLA-DMB"
+"56","CD83"
+"57","DOCK4"
+"58","PDE4DIP"
+"59","ARRB2"
+"60","RNF130"
+"61","PFKFB3"
+"62","NINJ1"
+"63","C1orf54"
+"64","ACP5"
+"65","VIM"
+"66","CARD16"
+"67","OGFRL1"
+"68","WIPF1"
+"69","MAFB"
+"70","NBN"
+"71","JARID2"
+"72","APOE"
+"73","TPP1"
+"74","SMAP2"
+"75","RGS2"
+"76","LGALS1"
+"77","UPP1"
+"78","STX11"
+"79","CD68"
+"80","PTPRE"
+"81","CTSD"
+"82","ARHGDIB"
+"83","RALA"
+"84","ZEB2"
+"85","ATP6V1F"
+"86","BTG1"
+"87","CTSL"
+"88","SLC2A3"
+"89","RHOG"
+"90","ASAH1"
+"91","THBS1"
+"92","GNA13"
+"93","RNASET2"
+"94","GPX1"
+"95","SLC16A3"
+"96","PSAP"
+"97","DDIT4"
+"98","SEC11A"
+"99","REL"
+"100","HLA-DMA"
+"101","ARL4C"
+"102","C6orf48"
+"103","GPR137B"
+"104","CREG1"
+"105","SDC2"
+"106","CYBA"
+"107","CTSS"
+"108","HIST3H2A"
+"109","FCGRT"
+"110","IL1R2"
+"111","CLEC2B"
+"112","HIF1A"
+"113","CTSB"
+"114","SLC44A1"
+"115","PID1"
+"116","SLC6A6"
+"117","CXCL3"
+"118","ID2"
+"119","GPX4"
+"120","CST3"
+"121","SGK1"
+"122","ARL6IP5"
+"123","SDCBP"
+"124","ATP13A3"
+"125","FAM49B"
+"126","CMTM6"
+"127","RGS10"
+"128","CARD19"
+"129","RIPK2"
+"130","RILPL2"
+"131","GRB2"
+"132","GSTO1"
+"133","AREG"

genesets/DEG_OE1.csv

 "","x"
 "1","SCGB3A1"
-"2","PIGR"
-"3","OLFM4"
-"4","FCGBP"
-"5","LTF"
-"6","WFDC2"
-"7","SLPI"
-"8","FAM3D"
-"9","PI3"
-"10","C15orf48"
-"11","MMP7"
-"12","SERPINB3"
-"13","ANKRD36C"
-"14","ZG16B"
-"15","CXCL6"
-"16","RHOV"
-"17","CRABP2"
-"18","ASS1"
-"19","TMEM45B"
-"20","CEACAM6"
-"21","S100A6"
-"22","TMSB4X"
-"23","ATP1B1"
-"24","RARRES3"
-"25","CP"
-"26","ELF3"
-"27","VSIG2"
-"28","TSPAN1"
-"29","BIK"
-"30","PDZK1IP1"
-"31","AGR3"
-"32","CEACAM5"
-"33","RNF39"
-"34","FTH1"
-"35","SRD5A3"
-"36","FOXO3"
-"37","LINC01207"
-"38","ANXA1"
-"39","TMEM165"
-"40","CYP3A5"
-"41","HIGD1A"
-"42","CCL28"
-"43","TSPAN13"
-"44","HIST1H2AC"
-"45","RAB11FIP1"
-"46","REEP3"
-"47","HIST1H2BC"
-"48","TSPAN3"
-"49","SERINC2"
-"50","HIST1H1C"
-"51","ZFP36L1"
+"2","LCN2"
+"3","PIGR"
+"4","OLFM4"
+"5","FCGBP"
+"6","LTF"
+"7","GDF15"
+"8","WFDC2"
+"9","FAM3D"
+"10","SLPI"
+"11","PI3"
+"12","DUOXA2"
+"13","MMP7"
+"14","CXCL17"
+"15","SERPINB3"
+"16","CXCL6"
+"17","ZG16B"
+"18","ANKRD36C"
+"19","GLUL"
+"20","RHOV"
+"21","DUSP5"
+"22","CRABP2"
+"23","ADGRF1"
+"24","CEACAM6"
+"25","ATP1B1"
+"26","ASS1"
+"27","TMEM45B"
+"28","S100A6"
+"29","TSPAN1"
+"30","CP"
+"31","ELF3"
+"32","BIK"
+"33","PDZK1IP1"
+"34","RARRES3"
+"35","VSIG2"
+"36","AGR3"
+"37","FOXO3"
+"38","SRD5A3"
+"39","CEACAM5"
+"40","LINC01207"
+"41","RNF39"
+"42","HIGD1A"
+"43","CYP3A5"
+"44","TSPAN13"
+"45","HIST1H2BC"
+"46","CCL28"
+"47","HIST1H2AC"
+"48","RAB11FIP1"
+"49","TMEM165"
+"50","ANXA1"
+"51","HIST1H1C"
+"52","ZFP36L1"

genesets/DEG_OE2.csv

@@ -2,19 +2,17 @@
 "1","AKR1C2"
 "2","IGFBP3"
 "3","DHRS9"
-"4","KRT6A"
-"5","FABP5"
-"6","KRT13"
-"7","HSPA1B"
-"8","UBR4"
-"9","SDC1"
-"10","HECTD1"
-"11","B4GALT4"
-"12","FA2H"
-"13","AKR1C3"
-"14","TMPRSS4"
-"15","IL1RN"
-"16","LYPD3"
-"17","MSLN"
-"18","HSPA1A"
-"19","AKAP12"
+"4","GPX2"
+"5","KRT6A"
+"6","FABP5"
+"7","KRT13"
+"8","SDCBP2"
+"9","KIAA1551"
+"10","UBR4"
+"11","HSPA1B"
+"12","SDC1"
+"13","IL1RN"
+"14","HECTD1"
+"15","LYPD3"
+"16","AKR1C3"
+"17","HSPA1A"

genesets/DEG_SM.csv

@@ -7,48 +7,46 @@
 "6","EPAS1"
 "7","ADAMTS4"
 "8","IFITM3"
-"9","GAPDH"
-"10","TINAGL1"
-"11","ADRA2A"
-"12","STEAP4"
-"13","SRGN"
-"14","IFITM2"
-"15","MT1A"
-"16","NGF"
-"17","ACTA2"
-"18","MCAM"
-"19","PDK4"
-"20","KCNE4"
-"21","MTHFD2"
-"22","CRISPLD2"
-"23","FOXC2"
-"24","ADAMTS1"
-"25","PROCR"
-"26","HES4"
-"27","SYNPO2"
-"28","PDGFRB"
-"29","TIMP3"
-"30","PPP1R14A"
-"31","TPM1"
-"32","COL4A1"
-"33","RGS16"
-"34","PI15"
-"35","MYLK"
-"36","LPP"
-"37","CDKN1A"
-"38","ZBTB38"
-"39","SLC25A4"
-"40","CTSC"
-"41","ISG15"
-"42","HIPK2"
-"43","NDUFS2"
-"44","C2orf40"
-"45","HES1"
-"46","HSPB1"
-"47","NR2F2"
-"48","ZFHX3"
-"49","ZNF503"
-"50","C8orf4"
-"51","KLF6"
-"52","SNAI2"
-"53","RHOB"
+"9","TINAGL1"
+"10","ADRA2A"
+"11","STEAP4"
+"12","IFITM2"
+"13","MT1A"
+"14","NGF"
+"15","ACTA2"
+"16","MCAM"
+"17","PDK4"
+"18","KCNE4"
+"19","MTHFD2"
+"20","CRISPLD2"
+"21","FOXC2"
+"22","ADAMTS1"
+"23","PROCR"
+"24","HES4"
+"25","SYNPO2"
+"26","PDGFRB"
+"27","TIMP3"
+"28","PPP1R14A"
+"29","TPM1"
+"30","COL4A1"
+"31","RGS16"
+"32","PI15"
+"33","MYLK"
+"34","LPP"
+"35","CDKN1A"
+"36","ZBTB38"
+"37","SLC25A4"
+"38","CTSC"
+"39","ISG15"
+"40","HIPK2"
+"41","NDUFS2"
+"42","C2orf40"
+"43","HES1"
+"44","HSPB1"
+"45","NR2F2"
+"46","ZFHX3"
+"47","ZNF503"
+"48","C8orf4"
+"49","KLF6"
+"50","SNAI2"
+"51","RHOB"

genesets/DEG_St.csv

@@ -21,10 +21,10 @@
 "20","AKAP12"
 "21","IER3"
 "22","PMP22"
-"23","COL6A2"
-"24","SERPING1"
-"25","CTSL"
-"26","MEG3"
+"23","SRGN"
+"24","COL6A2"
+"25","SERPING1"
+"26","CTSL"
 "27","SPARC"
 "28","BNIP3L"
 "29","MT2A"
@@ -92,22 +92,21 @@
 "91","ANKRD28"
 "92","GLIS3"
 "93","IL32"
-"94","JAG1"
-"95","NINJ1"
-"96","ARID5A"
-"97","CFH"
-"98","TBX3"
-"99","BST2"
-"100","GABARAPL1"
-"101","SERPINH1"
-"102","INSIG1"
-"103","PTP4A1"
-"104","ID3"
-"105","SERPINF1"
-"106","GADD45B"
-"107","ZFP36"
-"108","CXCL3"
-"109","TFPI2"
-"110","TM4SF1"
-"111","HSPA1A"
-"112","DUSP1"
+"94","NINJ1"
+"95","ARID5A"
+"96","CFH"
+"97","TBX3"
+"98","BST2"
+"99","GABARAPL1"
+"100","SERPINH1"
+"101","INSIG1"
+"102","PTP4A1"
+"103","ID3"
+"104","SERPINF1"
+"105","GADD45B"
+"106","ZFP36"
+"107","CXCL3"
+"108","TFPI2"
+"109","TM4SF1"
+"110","HSPA1A"
+"111","DUSP1"