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Commit 5c8f8159 authored by Achisha Saikia's avatar Achisha Saikia
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Updated description part 2

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# A unique identifier for the workflow package, text/underscores only
name: 'atac-seq-source'
# Who wrote this?
author: 'Achisha Saikia, Felix Perez, Peng Lian'
author: 'Felix Perez, Achisha Saikia, Peng Lian'
# A contact email address for questions
email: 'achisha.saikia@utsouthwestern.edu, felix.perez@utsouthwestern.edu, biohpc-help@utsouthwestern.edu'
email: 'felix.perez@utsouthwestern.edu, achisha.saikia@utsouthwestern.edu, biohpc-help@utsouthwestern.edu'
# A more informative title for the workflow package
title: 'ATAC-seq Source Workflow"
# A summary of the workflow package in plain text
This pipeline is designed for automated end-to-end quality control and processing of ATAC-seq. The pipeline can be run end-to-end, starting from raw FASTQ files all the way to peak calling and signal track generation using a single caper submit command. One can also start the pipeline from intermediate stages (for example, using alignment files as input). The pipeline supports both single-end and paired-end data as well as replicated or non-replicated datasets. The outputs produced by the pipeline include 1) formatted HTML reports that include quality control measures specifically designed for ATAC-seq and DNase-seq data, 2) analysis of reproducibility, 3) stringent and relaxed thresholding of peaks, 4) fold-enrichment and pvalue signal tracks.
description: |
# TODO: Please describe the workflow. (AS)
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......@@ -8,7 +8,7 @@ This repo is used to wrap the existing ATAC-seq pipeline listed below (Runner),
- The ATAC-seq Runner workflow, 'astrocyte-atac-runner] (https://git.biohpc.swmed.edu/s219741/astrocyte-atac-runner). This repo contains the original ATAC-seq pipeline developed by the ENCODE team.
## The ATAC-seq Runner workflow
<!-- TODO: Fill out intro to ATAC-seq pipeline. Which commands do we use to run this pipeline? What will the NextFlow script use? (AS) -->
<!-- TODO: Fill out intro to ATAC-seq pipeline. Which commands do we use to run this pipeline? What will the NextFlow script use? (AS) (DONE)-->
This pipeline is designed for automated end-to-end quality control and processing of ATAC-seq. The pipeline can be run end-to-end, starting from raw FASTQ files all the way to peak calling and signal track generation using a single caper submit command. One can also start the pipeline from intermediate stages (for example, using alignment files as input). The pipeline supports both single-end and paired-end data as well as replicated or non-replicated datasets. The outputs produced by the pipeline include 1) formatted HTML reports that include quality control measures specifically designed for ATAC-seq and DNase-seq data, 2) analysis of reproducibility, 3) stringent and relaxed thresholding of peaks, 4) fold-enrichment and pvalue signal tracks.
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