Commit bd6ef066 authored by dajiangliu's avatar dajiangliu Committed by zhanxw
Browse files


parent d2b292b9
......@@ -546,6 +546,13 @@ To generate empirical kinship (`--inVcf`) on both autosomal region and X chromos
NOTE: you need to provide a pedigree file (PED) in the above case, as `vcf2kinship` needs the sex information of samples to construct kinship for sex chromosome.
For modern genetic datasets, genotype data is often stored by chromosomes, with each chromosome stored in a separate VCF file. In this case, kinship matrix can be first calcualted separately for each chromosome, and then combined using the python script []( Specifically, if you generated two kinship matrices for chr1 chr2 (chr1.kinship, and chr2.kinship), you can run the python script to combine them, i.e.
python -o prefix chr1.kinship chr2.kinship
The resulting kinship matrix is equivalent to the kinship matrix calculated using the merged vcf files.
# Resources
## UCSC RefFlat Genes
Markdown is supported
0% or .
You are about to add 0 people to the discussion. Proceed with caution.
Finish editing this message first!
Please register or to comment