Commit 6f3c7a03 authored by Venkat Malladi's avatar Venkat Malladi
Browse files

Add in analysis for spikein normalized data.

parent f49458a0
......@@ -27,6 +27,9 @@ PARP-1 interacting snoRNA and DDX21
## Analysis of RNA-seq
- spike_in_correlation.py: Script to look at Spike-in counts to correlation
- spike_in_correlation.sh: Script to analyze spike-ins
- RNA-seq.Rmd: RNA-seq of data analysis regardless of spike-ins
## General Analysis
......
DDX21 RNA-seq Analsysis Spike-in
=====================================
## Setup and Imports
```{r init}
source("http://bioconductor.org/biocLite.R")
biocLite("RUVSeq")
install.packages("stringr")
install.packages("ggplot2")
install.packages("VennDiagram")
install.packages("reshape")
install.packages("eulerr")
install.packages("gplots")
install.packages("multcompView")
library(eulerr)
library(RUVSeq)
library(RColorBrewer)
library(edgeR)
library(gplots)
library(multcompView)
```
## Read in data
```{r spikein}
ddx21kd_rep1 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD-1.counts", header=F, sep='\t',col.names=c("GeneId", "DDX21KD_rep1"))
ddx21kd_rep2 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD-2.counts", header=F, sep='\t',col.names=c("GeneId", "DDX21KD_rep2"))
mut_ddx21_rep1 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD_pos_Mut_DDX21-1.counts", header=F, sep='\t',col.names=c("GeneId", "MUT_DDX21_rep1"))
mut_ddx21_rep2 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD_pos_Mut_DDX21-2.counts", header=F, sep='\t',col.names=c("GeneId", "MUT_DDX21_rep2"))
wt_ddx21_rep1 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD_pos_WT_DDX21-1.counts", header=F, sep='\t',col.names=c("GeneId", "WT_DDX21_rep1"))
wt_ddx21_rep2 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/DDX21_1KD_pos_WT_DDX21-2.counts", header=F, sep='\t',col.names=c("GeneId", "WT_DDX21_rep2"))
ddx21_rep1 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/LucKD-1.counts", header=F, sep='\t',col.names=c("GeneId", "DDX21_rep1"))
ddx21_rep2 <- read.csv("/Volumes/project/GCRB/Lee_Lab/s163035/MCF7_DDX21_inducibile_kd_Daeseok/htseq_counts/LucKD-2.counts", header=F, sep='\t',col.names=c("GeneId", "DDX21_rep2"))
merged_spikein <- Reduce(function(x, y) merge(x, y, all=TRUE),
list(ddx21_rep1, ddx21_rep2, ddx21kd_rep1, ddx21kd_rep2, mut_ddx21_rep1, mut_ddx21_rep2, wt_ddx21_rep1, wt_ddx21_rep2))
rownames(merged_spikein) <- merged_spikein$GeneId
merged_spikein_genes <- merged_spikein[grep("__", rownames(merged_spikein),invert = T),!(names(merged_spikein) %in% c('GeneId'))]
mapping <- read.csv("reference_annotations/mapping.txt", header=F, sep=',')
colnames(mapping) <- c("GeneId", "TranscriptId","GeneName","TranscriptName")
mapping_tmp <- data.frame(mapping$GeneId,mapping$GeneName)
mapping_genes <- mapping_tmp[!duplicated(mapping_tmp[,c('mapping.GeneId','mapping.GeneName')]),]
colnames(mapping_genes) <- c("GeneId", "GeneName")
rownames(mapping_genes) <- mapping_genes$GeneId
```
# Differential analysis setup
```{r setup}
# Filter out of at least 25 reads in at least 2 samples
filter <- apply(merged_spikein_genes, 1, function(x) length(x[x>25])>=2)
filtered <- merged_spikein_genes[filter,]
genes <- rownames(filtered)[grep("ENS", rownames(filtered))]
spikes <- rownames(filtered)[grep("gSpikein_ERC", rownames(filtered))]
x <- as.factor(rep(c("DDX21", "DDX21KD", "MUT_DDX21", "WT_DDX21"), each=2))
set <- newSeqExpressionSet(as.matrix(filtered), phenoData = data.frame(x, row.names=colnames(filtered)))
set1 <- RUVg(set, spikes, k=3)
pData(set1)
colors <- brewer.pal(4, "Set2")
plotRLE(set1, outline=FALSE, ylim=c(-1, 1), col=colors[x])
plotPCA(set1, col=colors[x], cex=1.2)
```
# Differential Analysis
```{r diff_analysis}
design <- model.matrix(~x + W_1, data=pData(set1))
y <- DGEList(counts=counts(set1), group=x)
y <- calcNormFactors(y, method="upperquartile")
y <- estimateGLMCommonDisp(y, design)
y <- estimateGLMTagwiseDisp(y, design)
fit <- glmFit(y, design)
# Differential Analysis 5% FDR
# Differential Analysis between groups KD and WT
lrt_kd <- glmLRT(fit, coef=2)
table_kd <- merge(topTags(lrt_kd, n=Inf)$table,mapping_genes,by="row.names")
det_kd <- decideTests(lrt_kd)
table_kd_up <- table_kd[det_kd == 1,]
table_kd_down <- table_kd[det_kd == -1,]
table_kd_up_down <- table_kd[det_kd != 0,]
write.table(table_kd_up, "tables/kd_up_genes_spikein.csv",sep=",", row.names = FALSE)
write.table(table_kd_down, "tables/kd_down_genes_spikein.csv",sep=",", row.names = FALSE)
# Differential Analysis between groups KD and MUT
lrt_mut <- glmLRT(fit, coef=3)
table_mut <- merge(topTags(lrt_mut, n=Inf)$table,mapping_genes,by="row.names")
det_mut <- decideTests(lrt_mut)
table_mut_up <- table_mut[det_mut == 1,]
table_mut_down <- table_mut[det_mut == -1,]
table_mut_up_down <- table_mut[det_mut != 0,]
write.table(table_mut_up, "tables/mut_up_genes_spikein.csv",sep=",", row.names = FALSE)
write.table(table_mut_down, "tables/mut_down_genes_spikein.csv",sep=",", row.names = FALSE)
# Differential Analysis between groups KD and WT rexpression
lrt_wt <- glmLRT(fit, coef=4)
table_wt <- merge(topTags(lrt_wt, n=Inf)$table,mapping_genes,by="row.names")
det_wt <- decideTests(lrt_wt)
table_wt_up <- table_wt[det_wt == 1,]
table_wt_down <- table_wt[det_wt == -1,]
table_wt_up_down <- table_wt[det_wt != 0,]
write.table(table_wt_up, "tables/wt_up_genes_spikein.csv",sep=",", row.names = FALSE)
write.table(table_wt_down, "tables/wt_down_genes_spikein.csv",sep=",", row.names = FALSE)
# Expression of genes found to be regulated by knockdown of DDX21
sample_cpm <- cpm(fit$fitted.values)
sample_cpm_kd <- sample_cpm[det_kd != 0,]
sample_cpm_kd_order_fc <- sample_cpm_kd[cluster$order,]
# Expression of DDX21 across replicates
jpeg('figures/ddx21_expression_cpm.jpg')
barplot(sample_cpm_kd_order_fc[58,], main="DDX21 Expression", xlab="Sample", ylab="CPM", names.arg=c("LUC 1", "LUC 2", "KD 1", "KD 2", "MUT 1", "MUT 2", "WT 1", "WT 2"),
col=c("red","red","black", "black", "dimgrey", "dimgrey", "lightgrey", "lightgrey"), ylim=c(0,300),cex.axis=1,las=2,lwd=4)
dev.off()
# Heat Map Fold Change Affected by KD and not affected for WT
ddx21_fc <- table_kd[(det_kd != 0 & det_wt == 0),]$logFC
wt_fc <- table_wt[(det_kd != 0 & det_wt == 0),]$logFC
mut_fc <- table_mut[(det_kd != 0 & det_wt == 0),]$logFC
fold_change <- data.frame(rownames(table_kd[(det_kd != 0 & det_wt == 0),]),table_kd[(det_kd != 0 & det_wt == 0),]$GeneId,table_kd[(det_kd != 0 & det_wt == 0),]$GeneName,ddx21_fc,wt_fc,mut_fc)
fold_change$max <- apply(abs(fold_change[,4:6]),1,max)
fold_change_max_abs_scale <- fold_change[,1:3]
fold_change_max_abs_scale$"LUCKD" <- 0
fold_change_max_abs_scale$"DDX21 KD" <- fold_change$ddx21_fc/fold_change$max
fold_change_max_abs_scale$"WT" <- fold_change$wt_fc/fold_change$max
fold_change_max_abs_scale$"MUT" <- fold_change$mut_fc/fold_change$max
names(fold_change_max_abs_scale) <- c("GID", "YORF", "NAME", "LUCKD", "DDX21KD", "WT", "MUT")
d <- dist(fold_change_max_abs_scale[,4:6], method = "euclidean")
fold_change_max_abs_scale_cluster <- hclust(d, "ward.D")
fold_change_max_abs_scale_cluster_sorted <- fold_change_max_abs_scale[fold_change_max_abs_scale_cluster$order,]
write.table(fold_change_max_abs_scale_cluster_sorted, "figures/DDX21_regulated_genes.cdt", sep="\t", row.names = FALSE)
tri.to.squ<-function(x)
{
rn<-row.names(x)
cn<-colnames(x)
an<-unique(c(cn,rn))
myval<-x[!is.na(x)]
mymat<-matrix(1,nrow=length(an),ncol=length(an),dimnames=list(an,an))
for(ext in 1:length(cn))
{
for(int in 1:length(rn))
{
if(is.na(x[row.names(x)==rn[int],colnames(x)==cn[ext]])) next
mymat[row.names(mymat)==rn[int],colnames(mymat)==cn[ext]]<-x[row.names(x)==rn[int],colnames(x)==cn[ext]]
mymat[row.names(mymat)==cn[ext],colnames(mymat)==rn[int]]<-x[row.names(x)==rn[int],colnames(x)==cn[ext]]
}
}
return(mymat)
}
# Fold change Boxplots
ddx21_fc_up <- table_kd[(det_kd == 1 & det_wt == 0),]$logFC
wt_fc_up <- table_wt[(det_kd == 1 & det_wt == 0),]$logFC
mut_fc_up <- table_mut[(det_kd == 1 & det_wt == 0),]$logFC
fold_change_up <- data.frame(table_kd[(det_kd == 1 & det_wt == 0),]$GeneId,table_kd[(det_kd == 1 & det_wt == 0),]$GeneName,ddx21_fc_up,wt_fc_up,mut_fc_up)
colnames(fold_change_up) <- c("GeneID", "NAME", "ddx21_fc", "wt_fc", "mut_fc")
up_not_recovered <- fold_change_up[which(fold_change_up$mut_fc > .25),]
up_moderatley_recovered <- fold_change_up[which(fold_change_up$mut_fc < .25),]
jpeg('figures/boxplot_ddx21_up_regulated_not_recovered_genes.jpg')
boxplot(2^up_not_recovered[,3:5], col=(c("yellow","yellow","yellow")), main="DDX21 Mut Not Recovered", ylab="Fold Change",outline=FALSE, notch=FALSE, names=c("KD", "WT", "MUT"),ylim = c(1,2.2),yaxt="n", cex.axis=1,las=2,lwd=4,lty=1)
axis(2, at=seq(1,2.2,.2))
dev.off()
jpeg('figures/boxplot_ddx21_up_regulated_moderatley_recovered_genes.jpg')
boxplot(2^up_moderatley_recovered[,3:5], col=(c("yellow","yellow","yellow")), main="DDX21 Mut Recovered", ylab="Fold Change",outline=FALSE, notch=FALSE, names=c("KD", "WT", "MUT"),ylim = c(0.6,2.2),yaxt="n", cex.axis=1,las=2,lwd=4,lty=1)
axis(2, at=seq(0.6,2.2,.2))
dev.off()
# Wilcox Rank Test
# Significance 0.05
up_not_recovered_df <- melt(up_not_recovered[,3:5])
mw <- pairwise.wilcox.test(up_not_recovered_df$value, up_not_recovered_df$variable, paired=TRUE, p.adj = "bonf")
mymat<-tri.to.squ(mw$p.value)
myletters<-multcompLetters(mymat,compare="<=",threshold=0.05,Letters=letters)
ddx21_fc_down <- table_kd[(det_kd == -1 & det_wt == 0),]$logFC
wt_fc_down <- table_wt[(det_kd == -1 & det_wt == 0),]$logFC
mut_fc_down <- table_mut[(det_kd == -1 & det_wt == 0),]$logFC
fold_change_down <- data.frame(table_kd[(det_kd == -1 & det_wt == 0),]$GeneId,table_kd[(det_kd == -1 & det_wt == 0),]$GeneName,ddx21_fc_down,wt_fc_down,mut_fc_down)
colnames(fold_change_down) <- c("GeneID", "NAME", "ddx21_fc", "wt_fc", "mut_fc")
down_not_recovered <- fold_change_down[which(fold_change_down$mut_fc < -.5),]
down_moderatley_recovered <- fold_change_down[which(fold_change_down$mut_fc >= -.5),]
jpeg('figures/boxplot_ddx21_down_regulated_not_recovered_genes.jpg')
boxplot(2^down_not_recovered[,3:5], col=(c("cyan","cyan","cyan")), main="DDX21 Mut Not Recovered", ylab="Fold Change",outline=FALSE, notch=FALSE, names=c("KD", "WT", "MUT"),ylim = c(0.4,1.2),yaxt="n", cex.axis=1,las=2,lwd=4,lty=1)
axis(2, at=seq(0.4,1.2,.2))
dev.off()
jpeg('figures/boxplot_ddx21_down_regulated_moderatley_recovered_genes.jpg')
boxplot(2^down_moderatley_recovered[,3:5], col=(c("cyan","cyan","cyan")), main="DDX21 Mut Recovered", ylab="Fold Change",outline=FALSE, notch=FALSE, names=c("KD", "WT", "MUT"),ylim = c(0.4,1.2),yaxt="n", cex.axis=1,las=2,lwd=4,lty=1)
axis(2, at=seq(0.4,1.2,.2))
dev.off()
# Wilcox Rank Test
# Significance 0.05
down_not_recovered_df <- melt(down_not_recovered[,3:5])
mw <- pairwise.wilcox.test(down_not_recovered_df$value, down_not_recovered_df$variable)
mymat<-tri.to.squ(mw$p.value)
myletters<-multcompLetters(mymat,compare="<=",threshold=0.05,Letters=letters)
```
"GID" "YORF" "NAME" "LUCKD" "DDX21KD" "WT" "MUT"
"6575" "ENSG00000148303.12" "RPL7A" 0 -1 -0.259291629899229 -0.449506630852822
"10470" "ENSG00000184949.11" "FAM227A" 0 -1 -0.256510773847042 -0.283375490758114
"373" "ENSG00000033327.8" "GAB2" 0 -1 -0.239354847680858 -0.560144654856979
"11660" "ENSG00000204628.7" "GNB2L1" 0 -1 -0.246815671182654 -0.572680416856648
"12493" "ENSG00000234857.2" "HNRNPUL2-BSCL2" 0 -1 -0.178004667273657 -0.160229776096772
"2024" "ENSG00000102317.13" "RBM3" 0 -1 -0.211193891137497 -0.590586756495283
"11977" "ENSG00000215030.4" "RPL13P12" 0 -1 -0.20685825263711 -0.341402192505837
"9513" "ENSG00000175061.13" "C17orf76-AS1" 0 -1 -0.329497605226728 -0.266769167961129
"12660" "ENSG00000241370.1" "RPP21" 0 -1 -0.32390386292658 -0.195820643510665
"13378" "ENSG00000265681.2" "RPL17" 0 -1 -0.321321315917947 -0.0681730650201384
"5575" "ENSG00000138175.8" "ARL3" 0 -1 -0.292833258659547 0.00402248791976751
"10210" "ENSG00000182628.8" "SKA2" 0 -1 -0.296782782410002 -0.614289760133776
"6726" "ENSG00000150540.9" "HNMT" 0 -1 -0.308854208925129 -0.269274497394847
"6702" "ENSG00000149806.6" "FAU" 0 -1 -0.303362046093514 -0.259572955021615
"11617" "ENSG00000204387.8" "C6orf48" 0 -1 -0.302564025712188 -0.230638405521634
"12589" "ENSG00000237883.1" "DGUOK-AS1" 0 -1 -0.355647780891432 -0.371456206230603
"12359" "ENSG00000230989.2" "HSBP1" 0 -1 -0.37042811757272 -0.475704424134617
"12731" "ENSG00000243678.7" "NME1-NME2" 0 -1 -0.365078803091647 -0.325081366484849
"13286" "ENSG00000261485.1" "PAN3-AS1" 0 -0.958749062606917 -0.393404539403541 -1
"4577" "ENSG00000130255.8" "RPL36" 0 -1 -0.420254497097943 -0.36805256119101
"10856" "ENSG00000188483.6" "IER5L" 0 -1 -0.396998465220999 -0.735883249907464
"10069" "ENSG00000181019.8" "NQO1" 0 -1 0.702246043804737 0.198263566163276
"2930" "ENSG00000111341.5" "MGP" 0 -1 0.075051473736394 -0.665905748214854
"7326" "ENSG00000158427.10" "TMSB15B" 0 -1 -0.0388351634481664 -0.319828397870383
"8256" "ENSG00000165732.8" "DDX21" 0 -1 -0.0612472237433242 -0.0322143784991788
"3610" "ENSG00000118181.6" "RPS25" 0 -1 -0.442736428130959 -0.00437386232622415
"12301" "ENSG00000229117.4" "RPL41" 0 -1 -0.438193803703272 -0.05103739584508
"4183" "ENSG00000125356.6" "NDUFA1" 0 -1 -0.457022249174771 -0.440331604432744
"7385" "ENSG00000159199.9" "ATP5G1" 0 -1 -0.467628416573922 -0.537289769429211
"6303" "ENSG00000144935.10" "TRPC1" 0 -0.946185459993292 -0.527526432642783 -1
"8917" "ENSG00000170091.6" "NSG2" 0 -0.942311136078745 -0.505382647495403 -1
"9590" "ENSG00000175768.8" "TOMM5" 0 -1 -0.539887572938722 -0.476311267933874
"5473" "ENSG00000137563.7" "GGH" 0 -1 -0.525947656702851 -0.482734753801642
"12946" "ENSG00000251928.1" "RNU6-585P" 0 -1 -0.519218284051912 -0.613134214673837
"1689" "ENSG00000100142.10" "POLR2F" 0 -1 -0.487627696420955 -0.290721803356872
"7182" "ENSG00000156482.6" "RPL30" 0 -1 -0.484677068221715 -0.438063056438316
"12489" "ENSG00000234741.3" "GAS5" 0 -1 -0.483432615922367 -0.262784574086306
"2563" "ENSG00000107223.8" "EDF1" 0 -1 -0.495359772187569 -0.60534137629071
"9589" "ENSG00000175764.10" "TTLL11" 0 -1 -0.503604371065877 -0.354138381805198
"10174" "ENSG00000182240.11" "BACE2" 0 -1 -0.506376781112603 -0.960120699618985
"10957" "ENSG00000189403.10" "HMGB1" 0 -1 -0.571087477535587 -0.526002102651654
"11952" "ENSG00000214595.7" "EML6" 0 -1 -0.567210844129215 -0.499783242280499
"10383" "ENSG00000184194.5" "GPR173" 0 -1 -0.578897803270124 -0.708692810265114
"1339" "ENSG00000087245.8" "MMP2" 0 -1 -0.589179914997358 0.658329932332413
"6089" "ENSG00000143222.7" "UFC1" 0 -1 -0.584578560020082 -0.43482430906772
"7882" "ENSG00000163644.10" "PPM1K" 0 -1 -0.586066257157298 -0.943404281974684
"4160" "ENSG00000124813.16" "RUNX2" 0 -0.942062123305916 -0.599400807055966 -1
"3377" "ENSG00000115758.8" "ODC1" 0 -0.974887643481951 -0.609289186726763 -1
"11606" "ENSG00000204316.8" "MRPL38" 0 -1 -0.601020540887356 -0.451969125552638
"12357" "ENSG00000230873.4" "STMND1" 0 -1 -0.609021778149115 -0.475548021318145
"3920" "ENSG00000122026.6" "RPL21" 0 -0.991828550600218 -0.617281303035962 -1
"10871" "ENSG00000188612.7" "SUMO2" 0 -1 -0.61911873328624 -0.545532799769525
"9225" "ENSG00000172428.6" "MYEOV2" 0 -1 -0.82524903969743 -0.497935572661993
"2034" "ENSG00000102543.10" "CDADC1" 0 -1 -0.766329452584357 0.0517729658707944
"11303" "ENSG00000198034.6" "RPS4X" 0 -1 -0.733246531821575 -0.906774728553396
"11289" "ENSG00000197958.8" "RPL12" 0 -1 -0.699903349006058 -0.975199043997027
"2338" "ENSG00000105329.5" "TGFB1" 0 -1 -0.697058167326636 -0.803809322744816
"10731" "ENSG00000187109.9" "NAP1L1" 0 -1 -0.697851309558922 -0.931129738072123
"13502" "ENSG00000269858.1" "EGLN2" 0 -1 -0.676345336463788 -0.543540081749014
"5436" "ENSG00000137267.5" "TUBB2A" 0 -1 -0.68167983628864 -0.522987187204123
"7841" "ENSG00000163479.9" "SSR2" 0 -1 -0.684285515098785 -0.367057886007922
"8370" "ENSG00000166441.8" "RPL27A" 0 -1 -0.635062720624566 -0.848853066427527
"4245" "ENSG00000125835.13" "SNRPB" 0 -1 -0.633759791490139 -0.845257062866378
"6653" "ENSG00000149260.10" "CAPN5" 0 -1 -0.633627467891963 -0.567557163075033
"7772" "ENSG00000163041.5" "H3F3A" 0 -1 -0.642452217688981 -0.853918662632115
"7862" "ENSG00000163584.13" "RPL22L1" 0 -1 -0.639582897673436 -0.799340749898383
"6973" "ENSG00000153574.8" "RPIA" 0 -1 -0.667498886320712 -0.793493511046235
"3634" "ENSG00000118515.7" "SGK1" 0 -1 -0.657521287809424 -0.791648246237144
"5737" "ENSG00000139579.8" "NABP2" 0 -1 -0.648917278129512 -0.573552165061392
"251" "ENSG00000013583.4" "HEBP1" 0 0.591073727672592 0.47531479873542 1
"6883" "ENSG00000152409.8" "JMY" 0 1 0.41341022244312 0.545572578809404
"4072" "ENSG00000124098.9" "FAM210B" 0 1 0.445027391385085 0.366894844293312
"12671" "ENSG00000241781.2" "AL161626.1" 0 1 0.440499292816783 0.858725306002536
"6110" "ENSG00000143367.11" "TUFT1" 0 1 0.456568782908754 0.549690868979347
"12692" "ENSG00000242299.1" "RP11-234A1.1" 0 1 0.466761662514677 0.509501467232065
"4689" "ENSG00000131069.15" "ACSS2" 0 0.901535815117477 0.475396904913733 1
"7573" "ENSG00000161202.13" "DVL3" 0 0.95635062679373 0.466507805802869 1
"9542" "ENSG00000175265.13" "GOLGA8A" 0 1 0.522205455885712 0.506343180653645
"4844" "ENSG00000132561.9" "MATN2" 0 1 0.495315235608566 0.0739617650233378
"12055" "ENSG00000220842.5" "RP11-572P18.1" 0 1 0.508612694369989 0.0297101345510955
"13094" "ENSG00000257084.1" "U47924.27" 0 1 0.506313233083149 0.451550383331052
"1720" "ENSG00000100276.9" "RASL10A" 0 1 0.56612216218496 0.738404052261622
"585" "ENSG00000057294.9" "PKP2" 0 1 0.572009540465615 0.297243493726589
"1462" "ENSG00000090581.5" "GNPTG" 0 1 0.573455896057002 0.722435540667495
"6066" "ENSG00000143061.13" "IGSF3" 0 1 0.542755063249404 0.635347635714383
"6331" "ENSG00000145348.12" "TBCK" 0 1 0.546214724915017 0.797498941364701
"7404" "ENSG00000159348.8" "CYB5R1" 0 1 0.554920124322913 0.75885831924491
"8188" "ENSG00000165288.10" "BRWD3" 0 1 0.559920332751134 0.435188732587294
"921" "ENSG00000072274.8" "TFRC" 0 1 0.675252938963592 0.783395355254841
"1096" "ENSG00000078114.14" "NEBL" 0 1 0.649378960211372 0.867935570369383
"12176" "ENSG00000225791.2" "TRAM2-AS1" 0 1 0.644213223679953 0.731071903819352
"6357" "ENSG00000145685.9" "LHFPL2" 0 1 0.637188852452039 0.703828909721836
"11224" "ENSG00000197563.5" "PIGN" 0 1 0.631661820520365 0.904497272701011
"9275" "ENSG00000172869.10" "DMXL1" 0 0.944838189382231 0.60411240666733 1
"4263" "ENSG00000125952.14" "MAX" 0 1 0.597417850789008 0.690864504646611
"7168" "ENSG00000156273.11" "BACH1" 0 1 0.622135789520344 0.697017935366309
"6642" "ENSG00000149177.8" "PTPRJ" 0 1 0.616735185428519 0.705112826115606
"11176" "ENSG00000197265.4" "GTF2E2" 0 1 0.615314921996045 0.89161530739901
"3708" "ENSG00000119574.8" "ZBTB45" 0 1 0.715610523345718 0.222061506202278
"118" "ENSG00000006831.9" "ADIPOR2" 0 1 0.74071479675078 0.834789826525939
"1954" "ENSG00000101639.14" "CEP192" 0 1 0.728095800585357 0.969218261558476
"5869" "ENSG00000140905.5" "GCSH" 0 1 0.733764136897481 0.26433116101688
"3057" "ENSG00000112414.10" "GPR126" 0 0.926649233108986 0.790117863227818 1
"6254" "ENSG00000144455.9" "SUMF1" 0 1 0.813957898386459 0.739629528750039
"6365" "ENSG00000145736.10" "GTF2H2" 0 1 0.780407116267696 0.807047660498584
"4701" "ENSG00000131171.8" "SH3BGRL" 0 1 -0.838995008612552 -0.343922528330215
"12547" "ENSG00000236824.1" "BCYRN1" 0 0.730981858140711 -0.353095135742429 -1
"4075" "ENSG00000124126.9" "PREX1" 0 1 -0.446668445616761 0.0244508293888281
"9336" "ENSG00000173391.4" "OLR1" 0 1 -0.469588846495123 0.198763622567183
"9437" "ENSG00000174307.5" "PHLDA3" 0 1 -0.45843290638089 -0.190505463820357
"9766" "ENSG00000177606.5" "JUN" 0 1 -0.11451285797351 -0.0457354291035481
"1964" "ENSG00000101825.7" "MXRA5" 0 1 -0.0549250691348075 0.0916066230917265
"4148" "ENSG00000124762.9" "CDKN1A" 0 1 -0.0486070893147965 -0.122787494853853
"6777" "ENSG00000151240.11" "DIP2C" 0 1 0.348128418047094 0.318603640507497
"2747" "ENSG00000109099.9" "PMP22" 0 1 0.280169235294298 0.986716267717722
"6714" "ENSG00000150093.14" "ITGB1" 0 1 0.30492351589521 0.639295211711425
"7780" "ENSG00000163083.5" "INHBB" 0 1 0.0638345729609293 0.38984919936399
"4362" "ENSG00000127415.8" "IDUA" 0 1 0.197321504752081 0.302555404350811
"10406" "ENSG00000184363.5" "PKP3" 0 1 0.201538414259564 0.609634615646393
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"Row.names","logFC","logCPM","LR","PValue","FDR","GeneId","GeneName"
"ENSG00000004399.8",-0.388545187072798,5.16127999292547,22.8370164296746,1.76336514900133e-06,0.000195335352311954,"ENSG00000004399.8","PLXND1"
"ENSG00000005249.8",-0.339450827500714,5.44931481217578,17.9829457540812,2.22892949963747e-05,0.00176974425474106,"ENSG00000005249.8","PRKAR2B"
"ENSG00000008256.11",-0.634627802888249,3.0920416588693,22.2888841193798,2.3456048640319e-06,0.000247840218556478,"ENSG00000008256.11","CYTH3"
"ENSG00000013810.14",-0.223147963947483,7.27257591756029,15.6815838132969,7.4950404826487e-05,0.00456336767772501,"ENSG00000013810.14","TACC3"
"ENSG00000023902.9",-0.298665763769791,4.41283855484215,10.2837860565762,0.00134204285485507,0.0386463326085729,"ENSG00000023902.9","PLEKHO1"
"ENSG00000029993.10",-0.317743089369358,8.13865140710528,15.9867306958028,6.37880106716334e-05,0.00401922988341999,"ENSG00000029993.10","HMGB3"
"ENSG00000033327.8",-0.460163502474351,5.45364102365709,33.5137404557781,7.07623181126595e-09,1.24614256614806e-06,"ENSG00000033327.8","GAB2"
"ENSG00000035499.8",-0.428563942265422,4.88036363132947,11.9010500343778,0.000561023093896636,0.0201682593107219,"ENSG00000035499.8","DEPDC1B"
"ENSG00000040633.8",-0.204975522234692,6.4063177047542,10.2376384750151,0.00137603641769131,0.0390521409781155,"ENSG00000040633.8","PHF23"
"ENSG00000044524.6",-1.90924044241459,0.67360754948571,44.1342040334747,3.06616106612948e-11,7.79940526006566e-09,"ENSG00000044524.6","EPHA3"
"ENSG00000056487.11",-1.01809485331528,0.56826348893502,13.3899214243456,0.000252979987842585,0.0117396388952897,"ENSG00000056487.11","PHF21B"
"ENSG00000058091.12",-0.657196766302798,2.37212382583651,17.7750796521157,2.48618391720316e-05,0.00191290860588531,"ENSG00000058091.12","CDK14"
"ENSG00000064042.13",-0.249354702810141,6.55142030403563,12.0738044519913,0.000511352445566349,0.0190867858486396,"ENSG00000064042.13","LIMCH1"
"ENSG00000064199.2",-0.378576623176124,3.68437191089638,10.4204083889269,0.00124630331076892,0.0365015400356542,"ENSG00000064199.2","SPA17"
"ENSG00000064225.8",-0.929959088293619,0.985309878048377,14.2603363456392,0.000159184168930496,0.00812845258152154,"ENSG00000064225.8","ST3GAL6"
"ENSG00000065154.7",-0.235702594732949,7.96861359835872,10.9953931025031,0.000913386382928959,0.0290423040646115,"ENSG00000065154.7","OAT"
"ENSG00000066629.12",-0.323517085857201,5.01120045067911,14.429714257772,0.000145488499058743,0.00774585280260037,"ENSG00000066629.12","EML1"
"ENSG00000067798.9",-0.837012716315076,2.75096278760554,20.1938130199805,6.99789021108716e-06,0.000658376848900638,"ENSG00000067798.9","NAV3"
"ENSG00000068489.8",-0.314532865093476,6.87105258734254,15.799597733123,7.04174780689376e-05,0.00433746403029115,"ENSG00000068489.8","PRR11"
"ENSG00000068745.10",-0.230988782981342,5.57037693785355,9.58285477887636,0.00196402782591417,0.0496830317067348,"ENSG00000068745.10","IP6K2"
"ENSG00000071054.11",-0.228492763656864,6.68013423992645,13.3288092758229,0.000261359429601533,0.0120067997491862,"ENSG00000071054.11","MAP4K4"
"ENSG00000074219.9",-0.344091386851809,6.03227482195242,20.1149008358938,7.29262936384284e-06,0.000678147939495787,"ENSG00000074219.9","TEAD2"
"ENSG00000075218.14",-0.281843166519001,6.18590978300719,13.0343491841287,0.000305829485634474,0.01329390447682,"ENSG00000075218.14","GTSE1"
"ENSG00000076382.12",-0.21944499250228,6.19059692113676,10.8770654805858,0.000973623876470819,0.0305502735968164,"ENSG00000076382.12","SPAG5"
"ENSG00000079819.12",-0.377565811726886,4.31590567819422,15.8218244702073,6.95951211933513e-05,0.00432560445570983,"ENSG00000079819.12","EPB41L2"
"ENSG00000082482.9",-1.06969627229539,0.833580004113497,17.952401088583,2.264985166845e-05,0.00178803656619442,"ENSG00000082482.9","KCNK2"
"ENSG00000083290.15",-0.310071288463596,4.95510707498141,14.6152305135477,0.000131844669514725,0.00715817541681528,"ENSG00000083290.15","ULK2"
"ENSG00000084676.11",-0.215285205944067,6.47924008709429,10.1601154258666,0.00143511635807364,0.0399853109421896,"ENSG00000084676.11","NCOA1"
"ENSG00000086548.8",-0.652145946263184,1.41400370429381,10.3498076249602,0.00129488179119981,0.0376832548388147,"ENSG00000086548.8","CEACAM6"
"ENSG00000087245.8",-1.41572600604463,-0.0479404082529271,10.8738424784738,0.00097531966693775,0.0305502735968164,"ENSG00000087245.8","MMP2"
"ENSG00000087586.13",-0.39716232620784,6.93570899392376,12.6380919691857,0.000377965549236608,0.0153797500693965,"ENSG00000087586.13","AURKA"
"ENSG00000087916.7",-0.523680448925211,4.73938498392686,21.6585009865343,3.25763080494078e-06,0.000333931468184079,"ENSG00000087916.7","SLC6A14"
"ENSG00000088325.11",-0.165037722556261,7.78570472672953,10.009515046599,0.00155733524582044,0.0418621466469463,"ENSG00000088325.11","TPX2"
"ENSG00000088727.8",-0.448880740204229,3.14246911154986,12.0355931108779,0.000521942237362817,0.0192833339741163,"ENSG00000088727.8","KIF9"
"ENSG00000088986.6",-0.31913055067781,7.61386259578243,16.4850926436841,4.90340970205699e-05,0.00319408281012034,"ENSG00000088986.6","DYNLL1"
"ENSG00000089685.10",-0.355248279433795,7.07505811720831,11.1624182837034,0.000834710460429206,0.0271696276882834,"ENSG00000089685.10","BIRC5"
"ENSG00000090889.10",-0.321844582891071,6.43815897469491,12.327810293259,0.000446259581393655,0.017315880254303,"ENSG00000090889.10","KIF4A"
"ENSG00000095739.7",-0.202724293836388,7.77812374176415,11.2317256650028,0.000804108435361999,0.0262357089504333,"ENSG00000095739.7","BAMBI"
"ENSG00000099260.6",-0.569567078429368,2.0957915129392,11.445902692662,0.000716518166614759,0.0242416096961092,"ENSG00000099260.6","PALMD"
"ENSG00000100078.3",-0.377561956208296,4.0473101127894,12.9317864083165,0.000323049344292912,0.0138236940598363,"ENSG00000100078.3","PLA2G3"
"ENSG00000100142.10",-0.309492615099271,5.88383574200583,11.2539268246793,0.000794547465337003,0.0259854856758787,"ENSG00000100142.10","POLR2F"
"ENSG00000101144.8",-0.390456651806016,4.50028539991167,11.9657087047775,0.000541885947114112,0.019743621669919,"ENSG00000101144.8","BMP7"
"ENSG00000101443.13",-0.371937445958034,4.11423479380299,13.5389394054506,0.000233664402636934,0.0111059316076849,"ENSG00000101443.13","WFDC2"
"ENSG00000101447.9",-0.293382968796632,5.90271787850347,14.7391898128493,0.000123453322490738,0.00678301935093109,"ENSG00000101447.9","FAM83D"
"ENSG00000102048.11",-0.751043337843498,3.11895855539044,33.1208959258027,8.66029952455879e-09,1.48697342836674e-06,"ENSG00000102048.11","ASB9"
"ENSG00000102317.13",-0.235604796751087,8.82877182696071,9.70861250491366,0.00183406434173624,0.0474560742470146,"ENSG00000102317.13","RBM3"
"ENSG00000102543.10",-0.641378838489409,1.88427309100092,11.5146879566329,0.000690484214049469,0.023652097666293,"ENSG00000102543.10","CDADC1"
"ENSG00000102554.9",-0.464960920953861,3.58833567818788,17.2885296490831,3.21119418834069e-05,0.00227365790572411,"ENSG00000102554.9","KLF5"
"ENSG00000103460.12",-0.924964977968159,3.31816379300096,59.6495308886614,1.13346277228721e-14,4.57918960004032e-12,"ENSG00000103460.12","TOX3"
"ENSG00000103485.13",-0.388296121941114,5.03847090114127,12.0116505297291,0.000528690160916677,0.0194173477282125,"ENSG00000103485.13","QPRT"
"ENSG00000105329.5",-0.307267850524738,5.76671818174755,13.2704734616429,0.000269619103604502,0.0121425836298736,"ENSG00000105329.5","TGFB1"
"ENSG00000105767.2",-0.512172963994702,2.61570358548765,12.7506556100354,0.000355884397149568,0.0148584440098677,"ENSG00000105767.2","CADM4"
"ENSG00000106070.13",-0.528770781520958,5.15329425658847,36.0995455776347,1.87490562153274e-09,3.48023021856402e-07,"ENSG00000106070.13","GRB10"
"ENSG00000106541.7",-0.24254149330208,8.97467063609795,17.8106885888409,2.44008649535897e-05,0.00191290860588531,"ENSG00000106541.7","AGR2"
"ENSG00000106789.8",-0.460689426448176,3.65577997923868,15.6782756227478,7.50816172951261e-05,0.00456336767772501,"ENSG00000106789.8","CORO2A"
"ENSG00000107223.8",-0.185231115682951,7.97450800257583,11.5919331178545,0.000662385212275257,0.0229760688783155,"ENSG00000107223.8","EDF1"
"ENSG00000107562.12",-0.216441761165585,6.15130063969727,10.9283418299433,0.000947042196887699,0.0299047623366654,"ENSG00000107562.12","CXCL12"
"ENSG00000108106.9",-0.386231768125331,7.19457271002355,13.7176594442502,0.000212447455801789,0.0102373898808002,"ENSG00000108106.9","UBE2S"
"ENSG00000109265.8",-0.436095401539668,3.07375187563138,11.4710659662064,0.000706881234731081,0.0240339619808568,"ENSG00000109265.8","KIAA1211"
"ENSG00000109881.12",-0.337439734401351,4.52952675287533,14.1942156351649,0.000164876574344677,0.00832626700440617,"ENSG00000109881.12","CCDC34"
"ENSG00000110375.2",-1.35906177301745,0.200887767834042,17.6975205436335,2.58963934238422e-05,0.00194378612060053,"ENSG00000110375.2","UPK2"
"ENSG00000110880.6",-0.191229405458286,6.95322564572818,10.4986328616737,0.00119462902192276,0.0352890843981313,"ENSG00000110880.6","CORO1C"
"ENSG00000111341.5",-0.257100514512089,5.73274929331844,10.1629118733131,0.00143294118952059,0.0399853109421896,"ENSG00000111341.5","MGP"
"ENSG00000111665.7",-0.240660465539173,5.3416629624161,10.0268820492783,0.00154271961301697,0.0418621466469463,"ENSG00000111665.7","CDCA3"
"ENSG00000111885.5",-0.470087131297415,3.20281983047149,14.369636160032,0.000150204989742183,0.00787486923320085,"ENSG00000111885.5","MAN1A1"
"ENSG00000112658.6",-0.191351122661191,7.15613270506505,11.8966488114784,0.000562350270530468,0.0201682593107219,"ENSG00000112658.6","SRF"
"ENSG00000112984.7",-0.33361177295096,6.95892466295108,11.0945463996025,0.000865819589565677,0.0279832891347627,"ENSG00000112984.7","KIF20A"
"ENSG00000113810.11",-0.216383432317039,7.01365173158676,12.7183375152534,0.000362087510067576,0.0150260847078194,"ENSG00000113810.11","SMC4"
"ENSG00000113924.7",-1.07141637921248,0.576464854043622,14.2516064163963,0.000159924247669331,0.0081337169153667,"ENSG00000113924.7","HGD"
"ENSG00000115290.5",-0.660209922808011,2.46465866116912,13.1010092964239,0.000295136723322329,0.0129688876616036,"ENSG00000115290.5","GRB14"
"ENSG00000115461.4",-0.575064961366684,6.01559298406611,38.4666961958488,5.56960513146356e-10,1.17698609362744e-07,"ENSG00000115461.4","IGFBP5"
"ENSG00000115525.12",-0.353552877747884,4.60049378494438,15.9982159506275,6.34022018941647e-05,0.00401922988341999,"ENSG00000115525.12","ST3GAL5"
"ENSG00000115738.5",-0.370200716308853,7.26989283362279,20.617345717399,5.60856535053742e-06,0.000538736039545329,"ENSG00000115738.5","ID2"
"ENSG00000115758.8",-0.213327719861605,7.99209388359102,12.2061173625234,0.000476330644003149,0.0180244565455296,"ENSG00000115758.8","ODC1"
"ENSG00000115963.9",-0.318832755057929,4.74478334235684,13.4217063148981,0.000248729350751325,0.0116605677881235,"ENSG00000115963.9","RND3"
"ENSG00000116106.7",-0.755799946622725,1.00879435191395,10.5942921680871,0.00113437320030501,0.0337998921461815,"ENSG00000116106.7","EPHA4"
"ENSG00000116991.6",-0.286024384244324,4.42131793724682,9.70814077313834,0.00183453519402772,0.0474560742470146,"ENSG00000116991.6","SIPA1L2"
"ENSG00000117115.8",-0.4408896547272,5.90041474179149,14.2646107091594,0.000158823068991818,0.00812845258152154,"ENSG00000117115.8","PADI2"
"ENSG00000117318.8",-0.272670106089123,6.13091698371556,15.5840994802814,7.89154351460539e-05,0.00473354767321483,"ENSG00000117318.8","ID3"
"ENSG00000117399.9",-0.298727026699746,7.23471617823537,20.6256068026933,5.58441680588989e-06,0.000538736039545329,"ENSG00000117399.9","CDC20"
"ENSG00000117632.16",-0.217917537384176,8.52181740990375,13.2414135101185,0.000273831338068695,0.0122919845088614,"ENSG00000117632.16","STMN1"
"ENSG00000118181.6",-0.415725968290929,10.1906196274314,17.0604989796435,3.62076376246519e-05,0.0024743687085185,"ENSG00000118181.6","RPS25"
"ENSG00000118515.7",-0.753437609861181,1.71988245464528,15.1162326256652,0.000101090298680508,0.00579514796608484,"ENSG00000118515.7","SGK1"
"ENSG00000120875.4",-0.766811326201334,3.61137631083661,44.6930111193144,2.3047853522942e-11,5.97330784888927e-09,"ENSG00000120875.4","DUSP4"
"ENSG00000121361.3",-0.882811742765158,1.29087343049526,16.4839132293139,4.90646092701945e-05,0.00319408281012034,"ENSG00000121361.3","KCNJ8"
"ENSG00000121858.6",-0.63654342545759,3.54839848312384,29.7689066937954,4.86736155113707e-08,7.59750889391123e-06,"ENSG00000121858.6","TNFSF10"
"ENSG00000121957.8",-0.308999641129453,6.20918388384646,11.9072551497648,0.000559157328642792,0.0201590159218829,"ENSG00000121957.8","GPSM2"
"ENSG00000121966.6",-0.930027834900211,1.63910266179758,22.7701862860738,1.82576214973784e-06,0.000200629351110392,"ENSG00000121966.6","CXCR4"
"ENSG00000122026.6",-0.178228306396223,9.33283435848952,10.8676142096511,0.000978605153072161,0.0305502735968164,"ENSG00000122026.6","RPL21"
"ENSG00000122952.12",-0.3486752751321,6.71844293546021,29.0195432426786,7.1651783825559e-08,1.08154824464602e-05,"ENSG00000122952.12","ZWINT"
"ENSG00000123728.5",-0.360657508501854,7.89246590682141,12.470708969173,0.000413383166600941,0.0162278749207685,"ENSG00000123728.5","RAP2C"
"ENSG00000124813.16",-0.88105985328307,1.22589714113175,14.9917202765612,0.000107983926042861,0.00607896396772434,"ENSG00000124813.16","RUNX2"
"ENSG00000125356.6",-0.265376504577254,7.18525087447538,13.7114170915407,0.000213154739801169,0.0102373898808002,"ENSG00000125356.6","NDUFA1"
"ENSG00000125835.13",-0.273245239885452,7.05242909500815,11.8860721910474,0.000565552597624728,0.0201777415090215,"ENSG00000125835.13","SNRPB"
"ENSG00000126787.8",-0.306045094922484,6.91206304884355,10.5968716477892,0.00113279166666855,0.0337998921461815,"ENSG00000126787.8","DLGAP5"
"ENSG00000127334.10",-0.260830114198819,5.91765114985876,9.61794885897542,0.00192684816965959,0.049146972542233,"ENSG00000127334.10","DYRK2"
"ENSG00000127863.11",-0.637997097283446,3.43320814879445,31.1287894755011,2.41463428851414e-08,3.90204901023885e-06,"ENSG00000127863.11","TNFRSF19"
"ENSG00000128294.11",-0.364665026499116,3.68420641197326,11.0337331558979,0.000894687951801099,0.0286466986152445,"ENSG00000128294.11","TPST2"
"ENSG00000128567.12",-0.479557260709438,4.61149336773838,29.64299654442,5.1939948259582e-08,8.01625987970358e-06,"ENSG00000128567.12","PODXL"
"ENSG00000128944.9",-0.30415897270492,5.61390473383909,12.3028407014857,0.00045226942183434,0.0174757207053265,"ENSG00000128944.9","KNSTRN"
"ENSG00000129195.11",-0.322044401096343,4.13029291462821,9.68506971724476,0.00185771338758282,0.0478753303786823,"ENSG00000129195.11","FAM64A"
"ENSG00000130255.8",-0.328782059041401,8.36472818960444,18.2964705315775,1.89057116771828e-05,0.00152676671764301,"ENSG00000130255.8","RPL36"
"ENSG00000130600.11",-1.46844288321093,2.21557882849569,41.2677209128929,1.3274294334776e-10,2.98910995053251e-08,"ENSG00000130600.11","H19"
"ENSG00000130821.11",-0.444161959242007,3.82585889737098,15.1624484924224,9.8645783591607e-05,0.0056932709387156,"ENSG00000130821.11","SLC6A8"
"ENSG00000130956.9",-0.439018084513081,3.67554405576983,13.7362404997088,0.000210356109651881,0.0101741250780924,"ENSG00000130956.9","HABP4"
"ENSG00000131747.10",-0.162095138357308,8.09157999215675,9.74247922791238,0.00180057880867676,0.0468850031301751,"ENSG00000131747.10","TOP2A"
"ENSG00000132688.10",-1.1471164195575,0.758037719415706,18.0607963360647,2.13961887436569e-05,0.00170870958478413,"ENSG00000132688.10","NES"
"ENSG00000132932.12",-0.445423425205244,3.97972287219149,10.7859678773081,0.0010227241433281,0.0314158501814646,"ENSG00000132932.12","ATP8A2"
"ENSG00000133519.8",-0.537840815023303,2.66443722024487,13.785833152592,0.000204875314527619,0.00994405413551721,"ENSG00000133519.8","ZDHHC8P1"
"ENSG00000133687.11",-0.331924107820986,5.56277282467845,11.9779162217515,0.000538347504102818,0.0196668652030753,"ENSG00000133687.11","TMTC1"
"ENSG00000133808.4",-1.12683206743992,0.207465387559733,13.041803313781,0.000304614647938499,0.0132831327113753,"ENSG00000133808.4","MICALCL"
"ENSG00000134057.10",-0.428041409191116,7.12014764069016,20.6875907148724,5.40652522259667e-06,0.000526695251472254,"ENSG00000134057.10","CCNB1"
"ENSG00000134215.11",-0.74105347542184,4.09894131143235,48.7621993425278,2.88955620927729e-12,8.62846610665932e-10,"ENSG00000134215.11","VAV3"
"ENSG00000134222.12",-0.383513396350325,5.30498179149021,23.0676892374719,1.56396944256567e-06,0.000174655969618553,"ENSG00000134222.12","PSRC1"
"ENSG00000134258.12",-0.878216860899369,0.821552067273908,12.4702073439856,0.000413494192069668,0.0162278749207685,"ENSG00000134258.12","VTCN1"
"ENSG00000134369.11",-0.43019060390297,3.52869374389478,11.2837855928313,0.000781869608486755,0.0256756185839892,"ENSG00000134369.11","NAV1"
"ENSG00000135374.5",-0.44155821774332,3.21479724384554,12.5887938181099,0.000388066505631977,0.0156129684726226,"ENSG00000135374.5","ELF5"
"ENSG00000135451.8",-0.37580684096679,6.25172132299381,22.2562620072148,2.38579453331893e-06,0.000250162394730297,"ENSG00000135451.8","TROAP"
"ENSG00000136153.15",-0.547493737392971,2.63260662601096,14.4572728303469,0.000143375156751903,0.00766303950639743,"ENSG00000136153.15","LMO7"
"ENSG00000136295.10",-0.213060200216485,6.05432601361376,9.6881576517414,0.00185459398970189,0.0478753303786823,"ENSG00000136295.10","TTYH3"
"ENSG00000136488.10",-5.23310678086451,1.10468030724796,125.865038600646,3.29122182532167e-29,4.52082229926184e-26,"ENSG00000136488.10","CSH1"
"ENSG00000137267.5",-0.593681304913952,1.7984304595763,9.78111309117078,0.00176313546861301,0.0463294600117508,"ENSG00000137267.5","TUBB2A"
"ENSG00000137563.7",-0.353646576381988,5.27961642308014,13.2010028996557,0.000279799349590571,0.0124547607034135,"ENSG00000137563.7","GGH"
"ENSG00000137869.9",-2.13226377032067,-0.125226528730357,21.5359903300027,3.47250143763779e-06,0.000350722645201417,"ENSG00000137869.9","CYP19A1"
"ENSG00000138175.8",-0.219690037795255,6.50758972606674,11.4734616149611,0.000705970612501114,0.0240339619808568,"ENSG00000138175.8","ARL3"
"ENSG00000138795.5",-0.538362040936668,2.11324012557914,10.1234514026535,0.00146394606253218,0.0406237638685697,"ENSG00000138795.5","LEF1"
"ENSG00000139289.9",-0.529692196323866,5.58794509048076,36.4754184585474,1.54603759416328e-09,2.99103836527138e-07,"ENSG00000139289.9","PHLDA1"
"ENSG00000139352.3",-1.25844864374108,3.02545784018273,93.026351649142,5.16026773586596e-22,3.22188352817522e-19,"ENSG00000139352.3","ASCL1"
"ENSG00000139579.8",-0.214783908570488,6.97324420008071,12.4139155642593,0.000426146404497306,0.0166293949209517,"ENSG00000139579.8","NABP2"
"ENSG00000139926.11",-0.346216302664549,4.74591314703713,11.9457508923597,0.000547721518127893,0.0199034464894305,"ENSG00000139926.11","FRMD6"
"ENSG00000140451.8",-0.557047214158093,2.23635950727654,11.4873962309812,0.000700697298886118,0.0239422340733824,"ENSG00000140451.8","PIF1"
"ENSG00000141499.12",-0.367788181406457,3.93180785410407,12.4388024471694,0.000420505323232133,0.0164560145866569,"ENSG00000141499.12","WRAP53"
"ENSG00000141668.5",-1.08432950344289,2.56939311627571,53.0477932913243,3.25530495519331e-13,1.06463973486989e-10,"ENSG00000141668.5","CBLN2"
"ENSG00000143013.8",-0.308628575651038,5.5224815315359,17.7908084857586,2.46571528752315e-05,0.00191290860588531,"ENSG00000143013.8","LMO4"
"ENSG00000143222.7",-0.218969576246689,7.12583736030232,14.8190127333751,0.000118336436710499,0.00658084734678305,"ENSG00000143222.7","UFC1"
"ENSG00000143590.9",-0.311125938317796,4.36929702977477,11.3048685332112,0.000773041218276036,0.0256069563864969,"ENSG00000143590.9","EFNA3"
"ENSG00000143815.10",-0.284129938508929,5.70684720307588,11.2806209241871,0.000783203566299611,0.0256756185839892,"ENSG00000143815.10","LBR"
"ENSG00000144331.14",-0.539901827112825,4.70368468171647,36.6457673762087,1.41666279312835e-09,2.82018552556681e-07,"ENSG00000144331.14","ZNF385B"
"ENSG00000144366.11",-0.511225309539794,2.46123786956972,11.0992624543948,0.000863620586033449,0.0279780480418761,"ENSG00000144366.11","GULP1"
"ENSG00000144677.10",-0.379441922147075,3.30435433809793,9.74080544324384,0.00180221910692577,0.0468850031301751,"ENSG00000144677.10","CTDSPL"
"ENSG00000144824.15",-0.856420670221048,1.81175711717623,21.868524287105,2.91984184198238e-06,0.000301555996552406,"ENSG00000144824.15","PHLDB2"
"ENSG00000144935.10",-0.655621785270032,2.14627363521257,14.7641685292485,0.000121828610945539,0.00672063373473064,"ENSG00000144935.10","TRPC1"
"ENSG00000145569.5",-0.866193564207982,0.504715696096991,9.63284909062944,0.00191127897561844,0.048888878974106,"ENSG00000145569.5","FAM105A"
"ENSG00000145632.10",-0.288806565357382,6.17426031626115,12.2652209379532,0.000461478578268897,0.0176570188052969,"ENSG00000145632.10","PLK2"
"ENSG00000146122.12",-0.636897399976708,2.57725396434431,18.7300584781833,1.50589891088225e-05,0.00125363802665931,"ENSG00000146122.12","DAAM2"
"ENSG00000146476.6",-0.21947842067561,9.68022659485444,14.8655033605995,0.000115455184164752,0.00644671711254889,"ENSG00000146476.6","C6orf211"
"ENSG00000146674.10",-0.732410851756808,1.24805881748168,11.85332681756,0.000575584271961955,0.020406697941233,"ENSG00000146674.10","IGFBP3"
"ENSG00000148303.12",-0.202394308554248,10.7157063241103,17.3551362185208,3.10059178427945e-05,0.00220672169683225,"ENSG00000148303.12","RPL7A"
"ENSG00000149260.10",-0.609606484386126,2.15972454619735,12.4880280747091,0.000409568291034083,0.0162127667021446,"ENSG00000149260.10","CAPN5"
"ENSG00000149806.6",-0.238618241477816,7.94702425304951,15.6565966281939,7.59472070984424e-05,0.00459564245244143,"ENSG00000149806.6","FAU"
"ENSG00000150540.9",-0.441002293691754,3.36901906546457,12.3001435625924,0.000452923454506132,0.0174757207053265,"ENSG00000150540.9","HNMT"
"ENSG00000150593.11",-0.171690242453371,8.81871709034555,9.87930568504474,0.0016714799934254,0.0447552615783455,"ENSG00000150593.11","PDCD4"
"ENSG00000151892.10",-0.184553005853246,9.11786061069695,13.1984702953357,0.000280177712387505,0.0124547607034135,"ENSG00000151892.10","GFRA1"
"ENSG00000153574.8",-0.313499267198251,5.00222755556112,12.687314176253,0.000368144682932606,0.0151402256430008,"ENSG00000153574.8","RPIA"
"ENSG00000156482.6",-0.250376744670256,10.119108987859,12.9414908909473,0.000321378958303071,0.0138236940598363,"ENSG00000156482.6","RPL30"
"ENSG00000157456.3",-0.295494741694321,6.07841946101004,12.8692700471339,0.00033402187082432,0.0141173059004396,"ENSG00000157456.3","CCNB2"
"ENSG00000158055.11",-0.393028718686853,3.16573454021732,10.0452229118794,0.00152743518730089,0.0416286701046926,"ENSG00000158055.11","GRHL3"
"ENSG00000158234.8",-0.334945143154338,4.1109733298229,10.7825238589282,0.00102462877703088,0.0314158501814646,"ENSG00000158234.8","FAIM"
"ENSG00000158427.10",-0.567537962908741,2.15183297952341,10.602436847275,0.00112938711877521,0.0337998921461815,"ENSG00000158427.10","TMSB15B"
"ENSG00000159199.9",-0.37299400373762,6.41775231780524,27.3971603206124,1.65674340062521e-07,2.34608529391628e-05,"ENSG00000159199.9","ATP5G1"
"ENSG00000159388.5",-0.3142135955061,5.79860743651856,13.0173763938479,0.000308613884332462,0.0133726192908224,"ENSG00000159388.5","BTG2"
"ENSG00000159921.10",-0.765877922035732,3.62784100974952,23.9999000340777,9.63407027521045e-07,0.00011310563188059,"ENSG00000159921.10","GNE"
"ENSG00000160014.12",-0.156636331320446,9.41658134020132,9.72852170166752,0.00181430352583192,0.0471101573361573,"ENSG00000160014.12","CALM3"
"ENSG00000160180.14",-0.642200456234195,3.1832294428227,25.155599728059,5.28858655043334e-07,6.72629859784744e-05,"ENSG00000160180.14","TFF3"
"ENSG00000160182.2",-1.06256299863666,5.2512498805978,130.534635231369,3.13022591871429e-30,5.37459790243243e-27,"ENSG00000160182.2","TFF1"
"ENSG00000160752.10",-0.256919421682099,6.57463642722617,13.2797271091662,0.000268291546639788,0.0121425836298736,"ENSG00000160752.10","FDPS"
"ENSG00000161642.13",-0.294041337063686,4.64450218469227,10.1717044645788,0.00142612374724989,0.0398966105747953,"ENSG00000161642.13","ZNF385A"
"ENSG00000162063.8",-0.246356381864931,6.42341765621492,14.7091874739778,0.00012543365097319,0.00686436904289934,"ENSG00000162063.8","CCNF"
"ENSG00000162073.9",-0.260247635308188,6.30089885492133,16.0214960600483,6.2627368914934e-05,0.00400116064844434,"ENSG00000162073.9","PAQR4"
"ENSG00000162300.7",-0.454463468809923,3.85508857077118,17.762508233907,2.5026663603688e-05,0.00191290860588531,"ENSG00000162300.7","ZFPL1"
"ENSG00000162621.5",-2.15911292953704,0.0261578327900258,37.996825425143,7.08598336418632e-10,1.45273235060393e-07,"ENSG00000162621.5","LRRC53"
"ENSG00000162636.11",-0.256172262995402,6.12276979199831,12.9361198863818,0.000322302364444494,0.0138236940598363,"ENSG00000162636.11","FAM102B"
"ENSG00000162909.13",-0.681549456622322,1.32694771920391,9.66181541991426,0.0018813760944863,0.0482137724512386,"ENSG00000162909.13","CAPN2"
"ENSG00000162981.12",-0.306051692110436,6.56214861187604,25.0641135822039,5.54553632836881e-07,6.924862455134e-05,"ENSG00000162981.12","FAM84A"
"ENSG00000163041.5",-0.321793592946159,7.00939558101517,11.7580585204821,0.000605803825137677,0.0213367213899772,"ENSG00000163041.5","H3F3A"
"ENSG00000163479.9",-0.196214490927328,7.99668112569589,12.9250844804201,0.000324208022885225,0.0138301906905325,"ENSG00000163479.9","SSR2"
"ENSG00000163584.13",-0.354850424603836,5.11315887553219,14.9356301534587,0.000111242089440001,0.0062368217981545,"ENSG00000163584.13","RPL22L1"
"ENSG00000163644.10",-0.299756125032643,4.86558445177154,10.0369675465701,0.00153429575529057,0.0417328445439036,"ENSG00000163644.10","PPM1K"
"ENSG00000164104.7",-0.333160288537196,7.98471168675218,16.8834689739837,3.97462345710939e-05,0.00267624646112032,"ENSG00000164104.7","HMGB2"
"ENSG00000164754.8",-0.168099208655788,8.73286399154105,10.7992627002891,0.00101540528041834,0.0314135291257348,"ENSG00000164754.8","RAD21"
"ENSG00000165424.6",-0.380500072997723,4.68727046923356,17.7616954886048,2.50373572532089e-05,0.00191290860588531,"ENSG00000165424.6","ZCCHC24"
"ENSG00000165626.12",-0.461581377004899,2.80548096401348,11.7270053089165,0.000615996367065487,0.0215850155561519,"ENSG00000165626.12","BEND7"
"ENSG00000165732.8",-1.96007231274783,7.74668507967284,852.528847925929,2.05017260981589e-187,2.8161170968431e-183,"ENSG00000165732.8","DDX21"
"ENSG00000166171.8",-0.460555729532734,3.44257047566528,15.4354543607032,8.53714833828322e-05,0.00509853345976775,"ENSG00000166171.8","DPCD"
"ENSG00000166173.9",-0.452896207740711,3.37977955250945,14.3516611342857,0.000151645840545815,0.00789017903688378,"ENSG00000166173.9","LARP6"
"ENSG00000166441.8",-0.234358412472071,9.40408314731789,16.0497766791324,6.16989033622792e-05,0.00396026232048723,"ENSG00000166441.8","RPL27A"
"ENSG00000167508.6",-0.374152475745238,5.12486436184594,13.8151952142625,0.000201698367842576,0.00984737237345848,"ENSG00000167508.6","MVD"
"ENSG00000167552.9",-0.465159542408843,6.32379061145594,48.2941436918003,3.66846165319618e-12,1.07212743124048e-09,"ENSG00000167552.9","TUBA1A"
"ENSG00000167553.10",-0.402147182713986,7.40870592339205,17.1910034710983,3.38033417438364e-05,0.00233327991051928,"ENSG00000167553.10","TUBA1C"
"ENSG00000167680.11",-0.690812349376864,2.31059499025535,17.7240028875138,2.55383725187728e-05,0.00193530889104984,"ENSG00000167680.11","SEMA6B"
"ENSG00000167693.12",-0.682894758111761,1.73240227352541,13.1468786303737,0.000287998613448706,0.0127200931007441,"ENSG00000167693.12","NXN"
"ENSG00000167767.9",-0.351872075144159,6.17024283291001,27.5716726705023,1.51379605454818e-07,2.21054316759858e-05,"ENSG00000167767.9","KRT80"
"ENSG00000168209.4",-0.311735887930896,5.27477711766355,15.4068737664173,8.6672442756275e-05,0.005131606352156,"ENSG00000168209.4","DDIT4"
"ENSG00000168389.13",-0.507279043184425,2.48086385460436,10.5005632691385,0.00119338159823559,0.0352890843981313,"ENSG00000168389.13","MFSD2A"
"ENSG00000168453.10",-0.30255582858814,5.14730224369371,12.6357095152288,0.000378447548300525,0.0153797500693965,"ENSG00000168453.10","HR"
"ENSG00000168785.3",-0.426828144380719,3.34761302446694,12.6659357514379,0.000372378111581937,0.0152686141513119,"ENSG00000168785.3","TSPAN5"
"ENSG00000168874.8",-0.865008922814444,1.71404635255613,20.1038983647348,7.33470209626674e-06,0.000678147939495787,"ENSG00000168874.8","ATOH8"
"ENSG00000169047.5",-0.725270168955114,4.3266051432518,55.5148176067653,9.27571833342533e-14,3.35292807968238e-11,"ENSG00000169047.5","IRS1"
"ENSG00000169246.12",-0.811807477488341,1.79850920017908,17.6329069140151,2.67912296140884e-05,0.0019796526863409,"ENSG00000169246.12","NPIPB3"
"ENSG00000169908.6",-0.58623732428418,1.90503487738648,11.0249482850295,0.000898937866226246,0.0287158384429854,"ENSG00000169908.6","TM4SF1"
"ENSG00000170091.6",-1.66442174186862,-0.708972857733827,13.3048861427615,0.000264715365745385,0.0120801669896299,"ENSG00000170091.6","NSG2"
"ENSG00000170396.6",-1.62643516395789,0.764632078329543,36.6128832830392,1.44076349624033e-09,2.82718962633674e-07,"ENSG00000170396.6","ZNF804A"
"ENSG00000171016.7",-0.397159025146255,3.76497164525116,12.2510246506029,0.000465002744603099,0.0176854595387386,"ENSG00000171016.7","PYGO1"
"ENSG00000171033.8",-0.305457497186128,4.86887433037351,13.3939442098083,0.000252437994277902,0.0117396388952897,"ENSG00000171033.8","PKIA"
"ENSG00000171522.5",-0.886901491602777,0.863300433335806,12.5674401850779,0.000392525870954776,0.0156736493123105,"ENSG00000171522.5","PTGER4"
"ENSG00000171617.9",-0.437289281734262,4.57533842008532,21.1621292558105,4.22021800598193e-06,0.000423130762993925,"ENSG00000171617.9","ENC1"
"ENSG00000172201.6",-0.413763986446024,4.25012795842351,14.5150440631559,0.000139044705583771,0.00746061748397924,"ENSG00000172201.6","ID4"
"ENSG00000172428.6",-0.278705694125904,5.73967263679787,9.7567228661535,0.00178668121065963,0.046746386875468,"ENSG00000172428.6","MYEOV2"
"ENSG00000172531.10",-0.197373740766524,8.23941407963573,12.0464139418806,0.000518921108339955,0.0192833339741163,"ENSG00000172531.10","PPP1CA"
"ENSG00000172551.6",-0.391076010915028,3.41747491363931,11.3034015906736,0.000773652220471476,0.0256069563864969,"ENSG00000172551.6","MUCL1"
"ENSG00000173848.14",-0.262079106218464,6.85570522846277,14.3052495470045,0.00015543081979665,0.00800341431322601,"ENSG00000173848.14","NET1"
"ENSG00000173930.8",-0.738411823270446,1.60784239276067,14.3731198521316,0.000149927341068139,0.00787486923320085,"ENSG00000173930.8","SLCO4C1"
"ENSG00000175061.13",-0.264314308488305,8.70867042289225,11.7925459862086,0.00059468350394893,0.0209989013116774,"ENSG00000175061.13","C17orf76-AS1"
"ENSG00000175063.12",-0.428043967465363,6.9491078126303,25.1189820946708,5.38996702348167e-07,6.79234743436186e-05,"ENSG00000175063.12","UBE2C"
"ENSG00000175175.4",-0.461307303394217,2.62303544053981,10.1955501478288,0.0014077995411552,0.0395434174478249,"ENSG00000175175.4","PPM1E"
"ENSG00000175183.5",-0.622586111484012,3.12458240129476,23.7821057482028,1.07880751697703e-06,0.000124525210531063,"ENSG00000175183.5","CSRP2"
"ENSG00000175745.7",-0.340795585122822,3.63711269478307,9.82324396280456,0.00172320144203708,0.0456301815540193,"ENSG00000175745.7","NR2F1"
"ENSG00000175764.10",-0.5099667237149,2.57073717653174,10.68077323184,0.00108254801660842,0.0328253411835173,"ENSG00000175764.10","TTLL11"
"ENSG00000175768.8",-0.434185426969012,4.06301360100382,10.0133553649473,0.00155409129940504,0.0418621466469463,"ENSG00000175768.8","TOMM5"
"ENSG00000175785.8",-0.464364887659183,3.14309462642773,13.2746551235628,0.000269018371363731,0.0121425836298736,"ENSG00000175785.8","PRIMA1"
"ENSG00000175793.10",-0.274996877126079,6.10034676882229,15.9588467668237,6.47345325478077e-05,0.0040602444706698,"ENSG00000175793.10","SFN"
"ENSG00000176014.8",-0.355904963330699,5.40734464557231,22.5767306279282,2.01915431909974e-06,0.000220119870850429,"ENSG00000176014.8","TUBB6"
"ENSG00000176165.7",-0.860963608619978,0.799473091481744,10.9533011992633,0.000934369971024437,0.0295725942903034,"ENSG00000176165.7","FOXG1"
"ENSG00000176463.9",-0.824082875433289,1.54503222706142,17.2206678201925,3.32796065610106e-05,0.00230873068546485,"ENSG00000176463.9","SLCO3A1"
"ENSG00000177189.8",-0.309909856078399,5.48057920622958,17.4674048493183,2.92276055324658e-05,0.00212418195552354,"ENSG00000177189.8","RPS6KA3"
"ENSG00000178372.6",-0.77612728513472,2.47014888996551,27.539378235372,1.53928384359969e-07,2.21054316759858e-05,"ENSG00000178372.6","CALML5"
"ENSG00000178531.4",-0.46578275265992,4.17467176140699,21.0171947567214,4.55179912261398e-06,0.000449809444231839,"ENSG00000178531.4","CTXN1"
"ENSG00000179456.9",-0.263493572152001,4.94324474489933,9.59619874043302,0.00194980591407455,0.0495056081991277,"ENSG00000179456.9","ZBTB18"
"ENSG00000180773.10",-0.663116463426466,2.13118641827677,15.2864188721697,9.23782999117929e-05,0.00544595848750381,"ENSG00000180773.10","SLC36A4"
"ENSG00000181019.8",-0.175291703465363,9.07798892103388,10.0181692107796,0.00155003467105791,0.0418621466469463,"ENSG00000181019.8","NQO1"
"ENSG00000181449.2",-1.11926288648839,2.96802670017379,73.6411872949896,9.36892033772091e-18,4.94967268303594e-15,"ENSG00000181449.2","SOX2"
"ENSG00000182240.11",-0.263635841960659,4.94315524621854,10.0980646056344,0.0014842512260797,0.0409391061072906,"ENSG00000182240.11","BACE2"
"ENSG00000182481.4",-0.232517551279928,8.99424583150223,10.6766733387705,0.00108494998740703,0.0328257115132664,"ENSG00000182481.4","KPNA2"
"ENSG00000182628.8",-0.238679070719421,8.17784742292461,11.891719693094,0.000563840395941407,0.0201690408298207,"ENSG00000182628.8","SKA2"
"ENSG00000182752.8",-2.14571478933289,-0.261762191545043,17.6776752551969,2.61679885487932e-05,0.00195349723209904,"ENSG00000182752.8","PAPPA"
"ENSG00000182853.7",-0.394349136823231,3.87292082128339,14.0322308770316,0.000179703835090265,0.00900880247737182,"ENSG00000182853.7","VMO1"
"ENSG00000183273.2",-0.505458714793247,2.25447539527315,9.66195663308064,0.0018812314831268,0.0482137724512386,"ENSG00000183273.2","CCDC60"
"ENSG00000183580.8",-0.608681868737891,2.79120663253558,19.003173649346,1.30501217581888e-05,0.00111339423894709,"ENSG00000183580.8","FBXL7"
"ENSG00000183778.13",-0.325432777268372,4.83676323639288,12.7088487794552,0.00036392939743809,0.015057030732559,"ENSG00000183778.13","B3GALT5"
"ENSG00000184194.5",-0.722261442928597,2.05084888017842,16.7667635605663,4.22671834880181e-05,0.00283210747508008,"ENSG00000184194.5","GPR173"
"ENSG00000184564.8",-0.736869671948646,2.35913476468104,21.9821028237389,2.75204795793072e-06,0.000286379778410124,"ENSG00000184564.8","SLITRK6"
"ENSG00000184949.11",-1.03061178250782,0.30229279343823,10.1483855467751,0.00144427672671289,0.0401590791864945,"ENSG00000184949.11","FAM227A"
"ENSG00000185361.4",-0.479323037004637,3.47517444417507,14.652875673677,0.000129237315358398,0.00704445938001171,"ENSG00000185361.4","TNFAIP8L1"
"ENSG00000185650.8",-0.26923980055439,7.26444691553415,12.1453707175302,0.000492098591199323,0.018468487018344,"ENSG00000185650.8","ZFP36L1"
"ENSG00000186960.6",-1.2638019519276,0.484943156923131,19.0557376977846,1.26955486372159e-05,0.00108991285050499,"ENSG00000186960.6","C14orf23"
"ENSG00000187109.9",-0.186270414362011,9.7273901083756,11.0727423414908,0.000876060201334975,0.0281816461956375,"ENSG00000187109.9","NAP1L1"
"ENSG00000187123.10",-0.357039906698139,4.68240516089653,12.5801302794457,0.000389869553444201,0.0156129684726226,"ENSG00000187123.10","LYPD6"
"ENSG00000187193.8",-0.563437372174557,2.52873014800682,13.9270596692458,0.000190042760811028,0.0094580701539865,"ENSG00000187193.8","MT1X"
"ENSG00000188229.5",-0.192414062456639,8.78710726263472,11.7336817361641,0.000613790459396662,0.0215627257040219,"ENSG00000188229.5","TUBB4B"
"ENSG00000188322.4",-0.474790435539119,4.47373344273406,22.5311458036988,2.06763893847528e-06,0.000223630617786586,"ENSG00000188322.4","SBK1"
"ENSG00000188483.6",-0.278741119458119,4.86200781464672,10.7351446786278,0.00105119783330156,0.0320872298627339,"ENSG00000188483.6","IER5L"
"ENSG00000188612.7",-0.371749255444533,8.25408708082483,11.9268774745566,0.000553298377872846,0.0200530514998982,"ENSG00000188612.7","SUMO2"
"ENSG00000188906.9",-0.45185631943597,2.77373799826406,10.2782338344172,0.00134608736787603,0.0386817072910986,"ENSG00000188906.9","LRRK2"
"ENSG00000189159.11",-0.228436933645742,7.20294449702976,13.3598781736219,0.000257065005070173,0.0118491439920936,"ENSG00000189159.11","HN1"
"ENSG00000189403.10",-0.344884897308643,10.1804050412619,20.9151028524613,4.80094439007583e-06,0.000471041229586297,"ENSG00000189403.10","HMGB1"
"ENSG00000196542.4",-0.429758042212707,3.34414117309059,13.2336870455655,0.000274962409066752,0.012302552608928,"ENSG00000196542.4","SPTSSB"
"ENSG00000197958.8",-0.216068755023697,9.91737256055244,11.0612157057362,0.000881523247314051,0.0282911292642659,"ENSG00000197958.8","RPL12"
"ENSG00000197977.3",-0.216288325319017,6.44698422752186,12.1607619573846,0.000488054348750411,0.0183668891354401,"ENSG00000197977.3","ELOVL2"
"ENSG00000198034.6",-0.227889286722293,10.6487097527185,10.2900446822899,0.0013374985088734,0.0385963855417751,"ENSG00000198034.6","RPS4X"
"ENSG00000198682.8",-0.452493827913503,2.89285918848439,10.3659624706626,0.00128359962175231,0.0374342344042245,"ENSG00000198682.8","PAPSS2"