diff --git a/README.md b/README.md index 43aef13ad2418025f80b674b9a4747c6203e068a..f7f1f7106c445bc330841424fe44d81ae30cc229 100755 --- a/README.md +++ b/README.md @@ -6,9 +6,9 @@ This is an R program to visualize and analyze -omics data such as those from mic ## Current version: V2.2. Tested R version: 4.3.2. -**Highlighted changes in V2.2:** Bulk RNA-seq analysis starting from a raw count table was added. DESeq2 is used for bulk RNA-seq data normalization and differential tests. clusterProfiler ORA and QEA analyses were added for gene/protein data. PLS-DA plot was added. Spearman and Kendall correlation plots were added. Analysis without erasing previous results was enabled. +**Highlighted updates in V2.2:** Bulk RNA-seq analysis starting from a raw count table was added. DESeq2 is used for bulk RNA-seq data normalization and differential tests. clusterProfiler ORA and QEA analyses were added for gene/protein data. PLS-DA plot was added. Spearman and Kendall correlation plots were added. Analysis without erasing previous results was enabled. Bug fixes. -**Highlighted changes in V2.1:** Metabolite Set Enrichment Analysis (MSEA), Pathway Analysis (MSPA), and Joint-Pathway Analysis (JointPA) were implemented using MetaboAnalystR 3.0.3. If a list of metabolite IDs is supplied, the Over Representation Analysis (ORA) can be done. If a differential test is specified, the Quantitative Enrichment Analysis (QEA) can be done. To do the analysis, metabolites need to be HMDB IDs or KEGG IDs. Alternatively, features can be metabolite names available in the MetaboAnalyst's compound database. See [MetaboAnalyst](https://www.metaboanalyst.ca/) for details about MSEA, MSPA, and JointPA. +**Highlighted updates in V2.1:** Metabolite Set Enrichment Analysis (MSEA), Pathway Analysis (MSPA), and Joint-Pathway Analysis (JointPA) were implemented using MetaboAnalystR 3.0.3. If a list of metabolite IDs is supplied, the Over Representation Analysis (ORA) can be done. If a differential test is specified, the Quantitative Enrichment Analysis (QEA) can be done. To do the analysis, metabolites need to be HMDB IDs or KEGG IDs. Alternatively, features can be metabolite names available in the MetaboAnalyst's compound database. See [MetaboAnalyst](https://www.metaboanalyst.ca/) for details about MSEA, MSPA, and JointPA. ## How to run this tool: